Yamamoto Taisuke, Kimura Takashi, Tamakoshi Akiko, Matsumoto Toshihiko
Department of Public Health, Hokkaido University Graduate School of Medicine, Kita-ku, Japan.
Department of Drug Dependence Research, National Center of Neurology and Psychiatry, Kodaira, Japan.
J Psychoactive Drugs. 2023 Jul-Aug;55(3):259-267. doi: 10.1080/02791072.2022.2105181. Epub 2022 Jul 27.
Methamphetamine is an illegal drug with the greatest burdens in Japan. Social and medical measures to combat methamphetamine dependence have been implemented, but no reports on changes in the characteristics of methamphetamine use disorder patients have been conducted. We aimed to describe these changes, and provide information on the results of social and medical measures. We concatenated cross-sectional surveys from 2000 to 2020 and analyzed biennial changes. Twenty-year data from 2000 to 2018 were age-weighted according to the age structure in 2020. We performed Cochran-Armitage trend tests for crude and age-weighted changes in patient variables. There was an increase in the number of patients with methamphetamine use disorder undergoing treatment and those with a history of drug-related arrests. Patients who achieved 1-year abstinence increased, and those diagnosed with psychotic disorders decreased. Patients with a history of non-drug-related arrests and without revealing their source of methamphetamine decreased. The ages of the patient population increased, and patients with a history of benzodiazepine misuse increased. Social measures linking methamphetamine users to psychiatric care may increase the number of patients who undergo treatment.
甲基苯丙胺是在日本造成负担最大的非法药物。针对甲基苯丙胺成瘾已实施了社会和医疗措施，但尚未有关于甲基苯丙胺使用障碍患者特征变化的报告。我们旨在描述这些变化，并提供社会和医疗措施的结果信息。我们汇总了2000年至2020年的横断面调查数据，并分析了每两年的变化情况。2000年至2018年的20年数据根据2020年的年龄结构进行了年龄加权。我们对患者变量的原始变化和年龄加权变化进行了 Cochr an - Armitage趋势检验。接受治疗的甲基苯丙胺使用障碍患者数量以及有与毒品相关逮捕史的患者数量有所增加。实现1年戒断的患者增加，被诊断患有精神障碍的患者减少。有与毒品无关逮捕史且未透露甲基苯丙胺来源的患者减少。患者群体的年龄增加，有苯二氮䓬类药物滥用史的患者增加。将甲基苯丙胺使用者与精神科护理联系起来的社会措施可能会增加接受治疗的患者数量。
