Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, 43124 Parma, Italy.
Org Biomol Chem. 2022 Aug 17;20(32):6464-6472. doi: 10.1039/d2ob01074g.
We report a solid-state structural investigation of diametric calix[6]arene-based phosphine gold(I) cavitands which are characterised by two specific, different 1,2,3-alternate conformations in solution and in the solid state. The effect of the specific orientation of phosphines, with respect to macrocycles, was studied in intramolecular cyclopropanation of 1,6-dienynes. The general applicability of these catalysts was disclosed, delivering a family of polycycles with high yields and functional group tolerance.
我们报告了一种基于直径型杯[6]芳烃的膦金（I）主体的固态结构研究，该主体在溶液中和固态中具有两种特定的、不同的 1,2,3-交替构象。我们研究了膦相对于大环的特定取向对 1,6-二炔的分子内环丙烷化反应的影响。这些催化剂的普遍适用性已被揭示，可用于高产率和官能团耐受性的多环化合物家族的合成。
