Vascular Health Research Group (ISV-Girona), Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), c/ Maluquer Salvador, 11 baixos, 17002, Girona, Catalonia, Spain.
Department of Medical Sciences, School of Medicine, Campus Salut, Universitat de Girona, Girona, Catalonia, Spain.
Sci Rep. 2022 Jul 27;12(1):12794. doi: 10.1038/s41598-022-16905-w.
There is an ongoing debate on the implementation of the COVID-19 passport throughout Europe. We sought to build and test a feasible prevention strategy to ensure low SARS-CoV transmission risk in public events. We conducted a non-randomised controlled study. The intervention group obtained a confidential digital certificate of very low capacity for transmitting SARS-CoV-2 and attended socio-cultural events in Girona (Spain) between 1 April and 21 May 2021. The primary care services and a network of pharmacies cooperated in providing the certification. A group of non-attendees was randomly selected from pseudonymised health records as controls. We estimated the incidences of SARS-CoV-2 infection and recorded the challenges in the process. Follow-up was complete for 1351 participants, who were matched with 4050 controls. Mean age of the study population was 31.1 years, and 53% of participants were women. Incidence rates of SARS-CoV infection at 14 days in the group of attendees and non-attendees were 15.9 and 17.7 per 100,000 person-days, respectively; the difference between incidences was - 1.8 (95% CI - 22.8, 19.3). Implementation problems were minor, and 89.2% of respondents to a survey were satisfied with the process. The incidence rate of SARS-CoV-2 infection was not different in the intervention and control groups. These results are in favour of establishing a COVID-19 certificate to attend public events, and connote feasibility of implementation at a population level.
在欧洲，关于实施 COVID-19 护照的问题一直存在争议。我们试图建立和测试一种可行的预防策略，以确保在公共活动中传播 SARS-CoV 的风险较低。我们进行了一项非随机对照研究。干预组获得了一份机密的数字证书，证明其传播 SARS-CoV-2 的能力非常低，并于 2021 年 4 月 1 日至 5 月 21 日在西班牙赫罗纳参加了社会文化活动。初级保健服务和一个网络药店合作提供认证。从假名健康记录中随机选择了一组未参加者作为对照组。我们估计了 SARS-CoV-2 感染的发病率，并记录了过程中的挑战。对 1351 名参与者进行了完整的随访，他们与 4050 名对照者相匹配。研究人群的平均年龄为 31.1 岁，53%的参与者为女性。在参与者和未参与者中，14 天的 SARS-CoV 感染发生率分别为每 100000 人天 15.9 和 17.7；发病率差异为-1.8（95%CI-22.8，19.3）。实施过程中出现的问题较小，对调查的 89.2%的受访者对该过程表示满意。干预组和对照组的 SARS-CoV-2 感染发病率无差异。这些结果支持建立 COVID-19 证书以参加公共活动，并暗示在人群层面上实施的可行性。
