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太平洋岛屿人群心脏代谢健康研究:理论基础与设计方案。

Pacific Islands Cohort on Cardiometabolic Health Study: rationale and design.

机构信息

University of Guam, UOG Station, 303 University Drive, Mangilao, Guam, 96923.

出版信息

BMC Public Health. 2022 Jul 27;22(1):1428. doi: 10.1186/s12889-022-13783-9.

DOI:10.1186/s12889-022-13783-9
PMID:35897002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9326143/
Abstract

BACKGROUND

Pacific Islanders, including those residing in the US Affiliated Pacific Islands (USAPI), experience some of the highest mortality rates resulting from non-communicable diseases (NCDs) worldwide. The Pacific Island Health Officers' Association declared a Regional State of Health Emergency in 2010 due to the epidemic of NCDs in the USAPI. Obesity, a known risk factor for NCDs, has become an epidemic among both children and adults in Micronesia and other parts of the USAPI. There is some recent information about overweight and obesity (OWOB) among young children in the USAPI, but there is no data looking at the relationship between children and their biological parents. The Pacific Islands Cohort on Cardiometabolic Health (PICCAH) Study aims to collect data on NCD lifestyle factors from two generations of families (n = 600 child-parent dyads or 1,200 participants) living in Guam, Pohnpei, and Palau.

METHODS

The PICCAH Study is an epidemiological study using community-based convenience sampling to recruit participants in USAPI of Guam, Palau, and Pohnpei. The goal is to recruit participant dyads consisting of 1 child plus their biological parent in Guam (500 dyads or 1,000 participants), Pohnpei (50 dyads or 100 participants), and Palau (50 dyads or 100 participants). All participants are having the following information collected: demographic, health, and lifestyle information; anthropometry; diet; physical activity; sleep; acanthosis nigricans; blood pressure; and serum levels of fasting plasma glucose, fasting insulin, glycated hemoglobin, total cholesterol, triglycerides, LDL, and HDL.

DISCUSSION

The PICCAH Study is designed to establish the baseline of a generational epidemiologic cohort with an emphasis on cardiometabolic risk, and to better understand the extent of DM and CVD conditions and related risk factors of those living in the USAPI jurisdictions of Guam, Pohnpei, and Palau. This study also serves to further build research capacity in the underserved USAPI Region.

摘要

背景

太平洋岛民,包括居住在美国属地太平洋岛屿(USAPI)的岛民,经历着全球一些最高的非传染性疾病(NCD)死亡率。由于 USAPI 的 NCD 流行,太平洋岛屿卫生官员协会于 2010 年宣布该地区进入卫生紧急状态。肥胖是 NCD 的一个已知危险因素,在密克罗尼西亚和 USAPI 的其他地区,肥胖已成为儿童和成年人的一种流行疾病。有关 USAPI 幼儿超重和肥胖(OWOB)的一些最新信息,但没有数据可以观察儿童与他们的亲生父母之间的关系。太平洋岛屿心血管代谢健康队列研究(PICCAH)旨在从两代家庭(n=600 个儿童-父母对子或 1200 名参与者)收集 NCD 生活方式因素的数据,这些家庭生活在关岛、波纳佩和帕劳。

方法

PICCAH 研究是一项采用社区便利抽样招募 USAPI 关岛、帕劳和波纳佩参与者的流行病学研究。目标是招募由关岛(500 对或 1000 名参与者)、波纳佩(50 对或 100 名参与者)和帕劳(50 对或 100 名参与者)的 1 名儿童及其亲生父母组成的参与者对子。所有参与者都将收集以下信息:人口统计学、健康和生活方式信息;人体测量学;饮食;体力活动;睡眠;黑棘皮病;血压;以及空腹血糖、空腹胰岛素、糖化血红蛋白、总胆固醇、甘油三酯、LDL 和 HDL 的血清水平。

讨论

PICCAH 研究旨在建立一个以心血管代谢风险为重点的代际流行病学队列的基线,并更好地了解生活在关岛、波纳佩和帕劳的 USAPI 管辖区的糖尿病和心血管疾病的严重程度以及相关风险因素。该研究还有助于进一步增强在服务不足的 USAPI 地区的研究能力。

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Nutrients. 2020 Aug 20;12(9):2527. doi: 10.3390/nu12092527.
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Best practices for community-engaged participatory research with Pacific Islander communities in the USA and USAPI: protocol for a scoping review.美国与美属太平洋岛屿社区开展社区参与式研究的最佳实践:一项范围综述的方案
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