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从儿童肥胖预测成人肥胖:一项系统评价与荟萃分析

Predicting adult obesity from childhood obesity: a systematic review and meta-analysis.

作者信息

Simmonds M, Llewellyn A, Owen C G, Woolacott N

机构信息

Centre for Reviews and Dissemination, University of York, York, UK.

Population Health Research Institute, St George's, University of London, London, UK.

出版信息

Obes Rev. 2016 Feb;17(2):95-107. doi: 10.1111/obr.12334. Epub 2015 Dec 23.

Abstract

A systematic review and meta-analysis was performed to investigate the ability of simple measures of childhood obesity such as body mass index (BMI) to predict future obesity in adolescence and adulthood. Large cohort studies, which measured obesity both in childhood and in later adolescence or adulthood, using any recognized measure of obesity were sought. Study quality was assessed. Studies were pooled using diagnostic meta-analysis methods. Fifteen prospective cohort studies were included in the meta-analysis. BMI was the only measure of obesity reported in any study, with 200,777 participants followed up. Obese children and adolescents were around five times more likely to be obese in adulthood than those who were not obese. Around 55% of obese children go on to be obese in adolescence, around 80% of obese adolescents will still be obese in adulthood and around 70% will be obese over age 30. Therefore, action to reduce and prevent obesity in these adolescents is needed. However, 70% of obese adults were not obese in childhood or adolescence, so targeting obesity reduction solely at obese or overweight children needs to be considered carefully as this may not substantially reduce the overall burden of adult obesity.

摘要

进行了一项系统评价和荟萃分析,以研究诸如体重指数(BMI)等儿童肥胖简单测量指标预测青少年期和成年期未来肥胖的能力。我们寻找了大型队列研究,这些研究使用任何公认的肥胖测量方法,在儿童期以及随后的青少年期或成年期测量肥胖情况。评估了研究质量。使用诊断性荟萃分析方法对研究进行汇总。荟萃分析纳入了15项前瞻性队列研究。BMI是任何研究中报告的唯一肥胖测量指标,共有200,777名参与者接受随访。肥胖儿童和青少年成年后肥胖的可能性是非肥胖者的约5倍。约55%的肥胖儿童在青少年期会继续肥胖,约80%的肥胖青少年成年后仍会肥胖,约70%在30岁以上仍会肥胖。因此,需要采取行动减少和预防这些青少年的肥胖。然而,70%的肥胖成年人在儿童期或青少年期并不肥胖,所以仅针对肥胖或超重儿童进行肥胖控制需要谨慎考虑,因为这可能无法大幅减轻成人肥胖的总体负担。

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