Department of Physical Education, Nanjing Xiao-Zhuang University, Nanjing 211171, China.
Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 333325, Taiwan.
Int J Environ Res Public Health. 2022 Jul 23;19(15):8985. doi: 10.3390/ijerph19158985.
The present study investigated the effects of acute aquatic high-intensity intermittent jumping (HIIJ) on blood pressure (BP) and arterial stiffness in postmenopausal women with different angiotensin-converting enzyme genotypes (ACE). We recruited 12 postmenopausal women carrying the ACE deletion/deletion (DD) genotype and 61 carrying the insertion/insertion or insertion/deletion (II/ID) genotype. The participants performed 12 trials of 30 s, 75% heart rate reserve (HRR) jumping, and 60 s, 50% HRR recovery, and 3 trials of 40 s upper limb resistance exercises were performed as fast as possible. The heart rate (HR) and BP were measured before exercise, immediately, 10 min, and 45 min after exercise. The brachial-ankle pulse wave velocity (baPWV) was measured before and after exercise. The systolic blood pressure (SBP) of the DD genotype increased more significantly than those with the II/ID genotype post-exercise (30.8 ± 4.48 vs. 20.4 ± 2.00 mmHg, = 0.038). The left and right sides of baPWV increased significantly after exercise (1444.8 ± 29.54 vs. 1473.4 ± 32.36 cm/s, = 0.020; 1442.1 ± 30.34 vs. 1472.0 ± 33.09, = 0.011), and there was no significant difference between the two groups. The HIIJ increased baPWV. The postmenopausal women with the DD genotype have a higher SBP increased post-exercise than those with II/ID genotype. These findings suggest that the aquatic exercise program has better effects in decreasing blood pressure in postmenopausal women with the II/ID genotype. Those with the DD genotype should pay attention to the risk of increasing blood pressure after aquatic HIIJ exercise.
本研究旨在探讨不同血管紧张素转换酶（ACE）基因型（DD 基因型和 II/ID 基因型）的绝经后女性进行急性水上高强度间歇跳跃（HIIJ）对血压（BP）和动脉僵硬度的影响。我们招募了 12 名携带 ACE 缺失/缺失（DD）基因型的绝经后女性和 61 名携带插入/插入或插入/缺失（II/ID）基因型的绝经后女性。参与者进行了 12 次 30 秒、75%心率储备（HRR）跳跃和 60 秒、50%HRR 恢复的跳跃，以及 3 次 40 秒上肢抗阻运动的尽可能快的跳跃。在运动前、运动后即刻、运动后 10 分钟和 45 分钟测量心率（HR）和血压。在运动前后测量臂踝脉搏波速度（baPWV）。DD 基因型的收缩压（SBP）在运动后比 II/ID 基因型增加得更显著（30.8 ± 4.48 与 20.4 ± 2.00mmHg， = 0.038）。运动后左右两侧的 baPWV 均显著增加（1444.8 ± 29.54 与 1473.4 ± 32.36cm/s， = 0.020；1442.1 ± 30.34 与 1472.0 ± 33.09， = 0.011），两组间无显著差异。HIIJ 增加了 baPWV。DD 基因型的绝经后女性运动后 SBP 升高幅度大于 II/ID 基因型。这些发现表明，水上 HIIJ 运动方案在降低 II/ID 基因型绝经后女性血压方面效果更好。DD 基因型的女性在进行水上 HIIJ 运动后应注意血压升高的风险。
