Division of Sport Science, Incheon National University, Incheon, Republic of Korea.
Sport Science Institute, Incheon National University, Incheon 22012, Republic of Korea.
Menopause. 2018 Dec;25(12):1442-1447. doi: 10.1097/GME.0000000000001154.
Postmenopausal women have increased arterial stiffness compared with premenopausal women. Regular physical activity including aerobic and resistance exercises are recommended to lower cardiovascular disease risk and to enhance musculoskeletal health in these women. This study examined the effect of combined circuit exercise on arterial stiffness in hypertensive postmenopausal women. Furthermore, it ascertained whether performing this exercise program is feasible in local public health centers with better accessibility than research and commercial facilities.
Among 24 hypertensive postmenopausal women, 16 finished this study in either the control (n = 8) or exercise (n = 8) group. Except for one participant who withdrew from the study due to the difficulty of the exercise program, seven participants withdrew due to reasons unrelated to the study. Circuit-type exercise (aerobic- and resistance-combined) program was applied to the exercise group, 60 min/d and 3 d/wk for 12 weeks under supervision. Brachial-ankle pulse wave velocity was measured to assess arterial stiffness.
In response to the combined exercise, brachial-ankle pulse wave velocity was significantly reduced in the hypertensive women (-0.7 m/s; P < 0.05). Weight, body mass index, and total cholesterol level were also significantly decreased after the exercise program (-2.1 kg, -0.8 kg/m, and -16 mg/dL, respectively; P < 0.05). In addition, changes in arterial stiffness were related to body adiposity, blood pressure, and blood lipid alterations (r = 0.61-0.70; P < 0.01).
Circuit combined exercise is an effective intervention to improve arterial stiffness in hypertensive postmenopausal women, and is feasible in local public health centers.
与绝经前女性相比，绝经后女性的动脉僵硬度增加。建议绝经后女性进行有规律的身体活动，包括有氧运动和抗阻运动，以降低心血管疾病风险并增强肌肉骨骼健康。本研究旨在探讨综合运动对高血压绝经后女性动脉僵硬度的影响。此外，还确定了在当地公共卫生中心实施这种运动方案是否可行，因为这些中心比研究和商业设施更容易获得。
在 24 名高血压绝经后女性中，有 16 名完成了该研究，分别为对照组（n=8）和运动组（n=8）。除了一名因运动方案难度而退出研究的参与者外，还有 7 名参与者因与研究无关的原因而退出。运动组接受了为期 12 周、每周 3 天、每天 60 分钟的综合运动（有氧和抗阻运动相结合）。通过测量肱踝脉搏波速度来评估动脉僵硬度。
综合运动后，高血压女性的肱踝脉搏波速度显著降低（-0.7m/s；P<0.05）。体重、体重指数和总胆固醇水平在运动方案后也显著降低（分别降低 2.1kg、0.8kg/m 和 16mg/dL；P<0.05）。此外，动脉僵硬度的变化与身体肥胖、血压和血脂变化相关（r=0.61-0.70；P<0.01）。
综合运动是改善高血压绝经后女性动脉僵硬度的有效干预措施，并且在当地公共卫生中心可行。
