Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Molecules. 2022 Jul 23;27(15):4705. doi: 10.3390/molecules27154705.
An efficient approach to the synthesis of diamides of 4,7-difluoro-1,10-phenanthroline-2,9-dicarboxylic acid was elaborated. Direct nucleophilic substitution with 4,7-dichloro-1,10-phenanthroline precursors opened access to difluoro derivatives in high yield. As a result, four new fluorinated ligands were prepared in up to 88% yield. Their structure was proved by a combination of spectral methods and X-ray data. A set of lanthanoid complexes was prepared to demonstrate the utility of new ligands. The structure of the complexes was studied in solid state (IR-spectroscopy, X-ray diffraction) and in solution (NMR-spectroscopy).
一种高效合成 4,7-二氟-1,10-菲啰啉-2,9-二羧酸二酰胺的方法被详细阐述。直接用 4,7-二氯-1,10-菲啰啉前体进行亲核取代反应，以高产率得到了二氟衍生物。结果，以高达 88%的产率制备了四个新的氟化配体。通过光谱方法和 X 射线数据的结合证明了它们的结构。还制备了一组镧系元素配合物以证明新配体的实用性。配合物的结构在固态（红外光谱，X 射线衍射）和溶液中（NMR 光谱）进行了研究。
