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2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2020美国心脏病学会/美国心脏协会瓣膜性心脏病患者管理指南：美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
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Aortic stenosis and angiodysplastic gastrointestinal bleeding: Heyde's disease.主动脉瓣狭窄和黏膜下血管发育不良性胃肠道出血：海德尔病。
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Blood. 1994 Apr 15;83(8):2171-9.
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Loss of the largest von Willebrand factor multimers from the plasma of patients with congenital cardiac defects.
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Changes in von Willebrand factor during cardiac surgery: effect of desmopressin acetate.心脏手术期间血管性血友病因子的变化：醋酸去氨加压素的作用。
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Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.鉴定一个切割位点，该位点指导对IIA型血管性血友病因子分子异常的免疫化学检测。
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下消化道出血的一种重要关联：一例海德综合征病例。

An Important Association With Lower Gastrointestinal Bleed: A Case of Heyde Syndrome.

作者信息

Dweik Anass, Al-Jabory Ola, Rasheed Waqas, Anees Muhammad Ali, Dweik Noor

机构信息

Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, USA.

Internal Medicine/Resident, Texas Tech University Health Sciences Center, Amarillo, USA.

出版信息

Cureus. 2022 Jun 23;14(6):e26232. doi: 10.7759/cureus.26232. eCollection 2022 Jun.

DOI:10.7759/cureus.26232
PMID:35898365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9308369/
Abstract

The association between aortic stenosis and angiodysplastic gastrointestinal bleed is known as Heyde syndrome. It was first described in 1958 and has since received further medical attention. We present a case of an 86-year-old lady with a history of severe aortic stenosis that was admitted with gastrointestinal bleeding secondary to colonic angiodysplasia. A review of the literature showed mixed opinions with respect to the idea of causation versus coincidence; both theories are valid. However, studies that supported causation had a bigger study population and overall seem to be more plausible.

摘要

主动脉瓣狭窄与血管发育异常性胃肠道出血之间的关联被称为海德综合征。它于1958年首次被描述，此后受到了更多的医学关注。我们报告一例86岁女性病例，该患者有严重主动脉瓣狭窄病史，因结肠血管发育异常继发胃肠道出血入院。文献综述显示，对于因果关系与巧合的观点存在不同意见；两种理论都有道理。然而，支持因果关系的研究有更大的研究群体，总体上似乎更有说服力。