Suppr超能文献

一名29岁男性在感染柯萨奇病毒后出现扩张型心肌病、局灶节段性肾小球硬化和贝尔麻痹的罕见病例。

A Rare Case of Dilated Cardiomyopathy, Focal Segmental Glomerulosclerosis, and Bell's Palsy in a 29-Year-Old Male After Coxsackievirus Infection.

作者信息

Ahmed Rafsan, Moaddab Amirhossein, Hussain Syed W, Viriya George, Graham-Hill Suzette

机构信息

Department of Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Department of Cardiology, State University of New York Downstate Health Sciences University, Brooklyn, USA.

出版信息

Cureus. 2022 Jun 24;14(6):e26285. doi: 10.7759/cureus.26285. eCollection 2022 Jun.

Abstract

Dilated cardiomyopathy (DCM) is a severe myocardial disease with diversified etiologies. Coxsackievirus serotype B (CV-B) is a known cause of infectious myocarditis that leads to DCM. The pathogenesis of CV-B myocarditis is complex and involves a combination of tissue destruction from viral proliferation and host immune response. Diagnosis is based on clinical findings and the presence of post-infection elevated titers of IgM antibodies to CV-B. Echocardiography is an important imaging modality that plays a key role in diagnosing DCM. Rare complications of coxsackievirus infection may include facial paralysis and chronic kidney disease with nephrotic syndrome. Here we present a rare case of a 29-year-old-male with recent Bell's palsy who presented with new-onset heart failure with left ventricular ejection fraction of 5% and focal segmental glomerulosclerosis nephrotic syndrome in the setting of elevated antibodies to CV-B.

摘要

扩张型心肌病(DCM)是一种病因多样的严重心肌疾病。柯萨奇B组病毒(CV-B)是已知的可导致感染性心肌炎进而引发DCM的病因。CV-B心肌炎的发病机制复杂,涉及病毒增殖引起的组织破坏和宿主免疫反应的共同作用。诊断基于临床症状以及感染后CV-B IgM抗体滴度升高。超声心动图是诊断DCM的重要影像学检查方法。柯萨奇病毒感染的罕见并发症可能包括面神经麻痹和伴有肾病综合征的慢性肾脏病。在此,我们报告一例罕见病例,一名29岁男性近期患贝尔麻痹,出现新发心力衰竭,左心室射血分数为5%,并在CV-B抗体升高的情况下出现局灶节段性肾小球硬化肾病综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abc/9308950/165eb68cba32/cureus-0014-00000026285-i01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验