• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates.

作者信息

Babson J R, Reed D J

出版信息

Biochem Biophys Res Commun. 1978 Jul 28;83(2):754-62. doi: 10.1016/0006-291x(78)91053-7.

DOI:10.1016/0006-291x(78)91053-7
PMID:358985
Abstract
摘要

相似文献

1
Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates.2-氯乙基亚硝基脲衍生的异氰酸酯对谷胱甘肽还原酶的失活作用。
Biochem Biophys Res Commun. 1978 Jul 28;83(2):754-62. doi: 10.1016/0006-291x(78)91053-7.
2
Inhibition of the ligase step of excision repair by 2-chloroethyl isocyanate, a decomposition product of 1,3-bis(2-chloroethyl)-1-nitrosourea.
Cancer Res. 1978 Apr;38(4):1064-9.
3
Isocyanate inactivation of yeast glutathione reductase & its modulation by oxidised glutathione and NADPH.异氰酸酯对酵母谷胱甘肽还原酶的失活作用及其受氧化型谷胱甘肽和还原型辅酶Ⅱ的调节
Biochem Soc Trans. 1996 May;24(2):325S. doi: 10.1042/bst024325s.
4
[Inactivation of glutathione reductase by quinones and nitrosocarbamides].
Ukr Biokhim Zh (1978). 1993 Jan-Feb;65(1):97-100.
5
In vitro inactivation of yeast glutathione reductase by tetramethylthiuram disulphide.二硫化四甲基秋兰姆对酵母谷胱甘肽还原酶的体外失活作用。
Eur J Biochem. 1995 Aug 1;231(3):667-72. doi: 10.1111/j.1432-1033.1995.tb20746.x.
6
Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas.氨甲酰化基团的化学结构及其与双功能烷基化和氨甲酰化亚硝基脲的骨髓毒性和抗胶质瘤活性的关系。
Cancer Res. 1985 Sep;45(9):4185-91.
7
Combined effect of nitrogen mustard and DNA repair inhibitor on the resistant tumor.氮芥与DNA修复抑制剂对耐药肿瘤的联合作用
Gan. 1974 Oct;65(5):465-6.
8
1,3-Bis(2-chloroethyl)-1-nitrosourea as thiol-carbamoylating agent in biological systems.1,3-双(2-氯乙基)-1-亚硝基脲作为生物系统中的硫醇-氨基甲酰化剂。
Methods Enzymol. 1995;251:173-88. doi: 10.1016/0076-6879(95)51120-2.
9
Pharmacology of chlorozotocin Nsc-178248), a new nitrosourea antitumor agent.新型亚硝基脲类抗肿瘤药物氯脲霉素(Nsc - 178248)的药理学
Cancer Treat Rep. 1976 Jun;60(6):801-5.
10
Differential inhibition of cellular glutathione reductase activity by isocyanates generated from the antitumor prodrugs Cloretazine and BCNU.抗肿瘤前药氯乙亚硝脲和卡莫司汀产生的异氰酸酯对细胞谷胱甘肽还原酶活性的差异抑制作用。
Biochem Pharmacol. 2005 May 15;69(10):1463-72. doi: 10.1016/j.bcp.2005.02.016.

引用本文的文献

1
A Preliminary Investigation towards the Risk Stratification of Allogeneic Stem Cell Recipients with Respect to the Potential for Development of GVHD via Their Pre-Transplant Plasma Lipid and Metabolic Signature.关于异基因干细胞受体通过移植前血浆脂质和代谢特征发生移植物抗宿主病(GVHD)可能性的风险分层的初步研究。
Cancers (Basel). 2019 Jul 25;11(8):1051. doi: 10.3390/cancers11081051.
2
Conserved molecular mechanisms underlying the effects of small molecule xenobiotic chemotherapeutics on cells.小分子外源性化学治疗药物对细胞作用的保守分子机制。
Mol Clin Oncol. 2016 Mar;4(3):326-368. doi: 10.3892/mco.2015.714. Epub 2015 Dec 16.
3
Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
与抗肿瘤药物洛莫司汀激活相关的氨甲酰化活性通过诱导ASK1依赖性内皮细胞死亡来抑制血管生成。
PLoS One. 2014 Jul 28;9(7):e103224. doi: 10.1371/journal.pone.0103224. eCollection 2014.
4
BCNU-induced gR2 defect mediates S-glutathionylation of Complex I and respiratory uncoupling in myocardium.BCNU 诱导的 gR2 缺陷介导心肌细胞复合体 I 的 S-谷胱甘肽化和呼吸解偶联。
Biochem Pharmacol. 2014 Jun 15;89(4):490-502. doi: 10.1016/j.bcp.2014.03.012. Epub 2014 Apr 1.
5
Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity.过氧化物代谢抑制剂增强抗坏血酸诱导的细胞毒性。
Free Radic Res. 2013 Mar;47(3):154-63. doi: 10.3109/10715762.2012.755263. Epub 2013 Jan 9.
6
Redox regulation of the intrinsic pathway in neuronal apoptosis.氧化还原调节神经元凋亡的内在途径。
Antioxid Redox Signal. 2011 Apr 15;14(8):1437-48. doi: 10.1089/ars.2010.3596. Epub 2011 Jan 8.
7
Superoxide Enhances the Antitumor Combination of AdMnSOD Plus BCNU in Breast Cancer.超氧阴离子增强 AdMnSOD 联合 BCNU 对乳腺癌的抗肿瘤作用。
Cancers (Basel). 2010 Feb 12;2(1):68-87. doi: 10.3390/cancers2010068.
8
Enhancing the antitumor activity of adriamycin and ionizing radiation.增强阿霉素和电离辐射的抗肿瘤活性。
Cancer Res. 2009 May 15;69(10):4294-300. doi: 10.1158/0008-5472.CAN-09-0396. Epub 2009 Apr 28.
9
Increased oxidative stress created by adenoviral MnSOD or CuZnSOD plus BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) inhibits breast cancer cell growth.腺病毒介导的锰超氧化物歧化酶或铜锌超氧化物歧化酶与卡莫司汀(1,3-双(2-氯乙基)-1-亚硝基脲)共同作用产生的氧化应激增加会抑制乳腺癌细胞的生长。
Free Radic Biol Med. 2008 Mar 1;44(5):856-67. doi: 10.1016/j.freeradbiomed.2007.11.009. Epub 2007 Nov 28.
10
Rapid activation of antioxidant defenses by nerve growth factor suppresses reactive oxygen species during neuronal apoptosis: evidence for a role in cytochrome c redistribution.神经生长因子对抗氧化防御的快速激活可在神经元凋亡过程中抑制活性氧:细胞色素c重新分布作用的证据
J Neurosci. 2007 Oct 17;27(42):11315-26. doi: 10.1523/JNEUROSCI.3590-07.2007.