Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, Chennai, 600073 Tamil Nadu, India.
Department of Mechanical Engineering, Chandigarh University, Mohali-140413, Punjab, India.
Biomed Res Int. 2022 Jul 18;2022:3234484. doi: 10.1155/2022/3234484. eCollection 2022.
People with hematologic malignancies (HM) frequently postulate intensive care unit (ICU) hospitalization due to organ damage caused by the disease process or treatment-related consequences. This study is aimed at looking at mortality and sign factors in adult patients with hematologic malignancy (HM) who have been hospitalized in the ICU. Death was one quality indicator; researchers used a machine learning approach to find determinants of death. As per the study, there have been 206 patients hospitalized in the ICU (mean age: 51.3 ± 13.6 years; 60% male). The average length of stay was three days, with 14.1% requiring extended ICU commitment. ICU death was 45.6% at 30 days, 62.6% at sixty days, and 74.3% at twelve months, rising to 59.2% at thirty days, 62.6% at sixty days, and 74.3% at twelve months. Ventilation systems and vasodilating medication were linked to higher ICU death, but admission to the ICU surgically and experiencing malignancies are linked with lower death rates. Patients with HM who are hospitalized in the ICU have a high mortality rate (45.6%), which rises to 74.3% after a year. Serious illness, postsurgical hospitalization, and malignancy were revealed as determinants of patient outcomes in multivariate analyses.
患有血液恶性肿瘤(HM)的人经常由于疾病过程或治疗相关后果引起的器官损伤而需要入住重症监护病房(ICU)。本研究旨在研究入住 ICU 的成年血液恶性肿瘤(HM)患者的死亡率和标志因素。死亡是一个质量指标;研究人员使用机器学习方法来寻找死亡的决定因素。根据该研究,有 206 名患者入住 ICU(平均年龄:51.3 ± 13.6 岁;60%为男性)。平均住院时间为三天,14.1%需要延长 ICU 入住时间。30 天、60 天和 12 个月的 ICU 死亡率分别为 45.6%、62.6%和 74.3%,而 30 天、60 天和 12 个月的 ICU 死亡率分别为 59.2%、62.6%和 74.3%。通气系统和血管扩张药物与较高的 ICU 死亡率相关,但 ICU 手术后住院和恶性肿瘤与较低的死亡率相关。入住 ICU 的 HM 患者死亡率较高(45.6%),一年后死亡率上升至 74.3%。在多变量分析中,严重疾病、手术后住院和恶性肿瘤被揭示为患者预后的决定因素。