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病例报告:一名绝经后糖尿病女性反复发生多次尿路感染:抗菌药物敏感性争议

Case Report: Urinary Tract Infection in a Diabetic Postmenopausal Woman With Multiple Episodes of Recurrence: An Antimicrobial Susceptibility dispute.

作者信息

Khalid Farah, Bushra Rabia, Ghayas Sana, Mushtaque Madiha

机构信息

Department of Pharmacy Practice, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan.

Department of Pharmaceutics, Dow College of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan.

出版信息

Clin Med Insights Case Rep. 2022 Jul 21;15:11795476221112819. doi: 10.1177/11795476221112819. eCollection 2022.

Abstract

Urinary tract infection (UTI) is caused by bacteria growing in urine and affect kidneys, bladder, ureters, and urethra. Women with diabetes are at high risk of developing UTI. This is a case of a 60-year-old postmenopausal woman with uncontrolled type-I diabetes mellitus and hypertension, who presented with an acute onset of dysuria, burning micturition, and increased frequency. This case highlights the shortfall in the preliminary management plan of performing imperative clinical laboratory investigations including urine detailed report (DR), urine culture and sensitivity(C/S), and plasma glucose testing to initiate antimicrobial treatment. UTI requires to be treated precisely in diabetic patients with the help of a comprehensive diagnosis for signs of dysuria, frequent urination, and pelvic pain. The treatment of UTIs should always begin with culture and sensitivity analysis while the patient is symptomatic, to initiate antimicrobial treatment. Comorbidities should be managed appropriately during treatment to achieve desired therapeutic outcomes.

摘要

尿路感染(UTI)是由尿液中生长的细菌引起的,会影响肾脏、膀胱、输尿管和尿道。糖尿病女性患UTI的风险很高。这是一例60岁的绝经后女性病例,患有未控制的I型糖尿病和高血压,出现了排尿困难、尿痛和尿频的急性发作。该病例凸显了在进行必要的临床实验室检查(包括尿液详细报告(DR)、尿培养和药敏试验(C/S)以及血浆葡萄糖检测)以启动抗菌治疗的初步管理计划中的不足。在糖尿病患者中,需要借助对排尿困难、尿频和盆腔疼痛症状的全面诊断来精确治疗UTI。在患者出现症状时,UTI的治疗应始终从培养和药敏分析开始,以启动抗菌治疗。在治疗期间应适当管理合并症,以实现理想的治疗效果。

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Recurrent UTIs and cystitis symptoms in women.女性复发性尿路感染和膀胱炎症状。
Aust J Gen Pract. 2021 Apr;50(4):199-205. doi: 10.31128/AJGP-11-20-5728.
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Risk factors and predisposing conditions for urinary tract infection.尿路感染的风险因素及易感条件。
Ther Adv Urol. 2019 May 2;11:1756287218814382. doi: 10.1177/1756287218814382. eCollection 2019 Jan-Dec.

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