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成人患者在癫痫监测病房中注意力缺陷多动障碍的识别率低。

Low recognition of attention deficit hyperactivity disorder in adult patients admitted to the Epilepsy Monitoring Unit.

机构信息

Department of Neurology, Baylor College of Medicine, Houston, Texas, USA.

Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.

出版信息

Brain Behav. 2022 Aug;12(8):e32731. doi: 10.1002/brb3.2731. Epub 2022 Jul 27.

DOI:10.1002/brb3.2731
PMID:35899366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9392548/
Abstract

INTRODUCTION

Adult patients with epilepsy (PWE) have an 18% prevalence of comorbid attention deficit hyperactivity disorder (ADHD) compared to a prevalence of 2%-5% in the general population. Recognition of this dual diagnosis is important since stimulant therapy is both safe and effective in this population.

METHODS

Here, we aim to determine if PWE have adequate documentation for comorbid ADHD when being admitted to the Epilepsy Monitoring Unit (EMU). A retrospective review was conducted at the Baylor St. Luke's Medical Center EMU for patients presenting between July 2017 and November 2020. Patients were divided into two groups: Group I-patients without a documented ADHD diagnosis or ADHD medications and Group II-patients with a documented ADHD diagnosis and/or taking medications indicated specifically for ADHD.

RESULTS

Of 524 individual patients who presented to the EMU, only 25 patients (4.8%) had documentation of a diagnosis of ADHD and/or ADHD medications (Group II). The proportion of patients in Group II did not significantly differ based on the EMU diagnosis. However, there was a significantly greater number of other psychiatric diagnoses (p = .005) and a greater number of psychiatric medications prescribed (p < .001) in patients in Group II.

CONCLUSION

Our study suggests that ADHD is underrecognized and underdiagnosed in patients presenting to the EMU, and screening tools may be useful to help clinicians address seizure comorbidities such as ADHD.

摘要

简介

与普通人群中 2%-5%的患病率相比,成年癫痫患者(PWE)的共患注意缺陷多动障碍(ADHD)患病率为 18%。认识到这一双重诊断很重要,因为兴奋剂疗法在这一人群中既安全又有效。

方法

在这里,我们旨在确定癫痫监测单元(EMU)入院的 PWE 是否有共患 ADHD 的充分记录。在贝勒圣卢克医疗中心 EMU 对 2017 年 7 月至 2020 年 11 月期间就诊的患者进行了回顾性研究。患者分为两组:无记录的 ADHD 诊断或 ADHD 药物治疗的组 I 患者和有记录的 ADHD 诊断和/或服用特定 ADHD 药物的组 II 患者。

结果

在 524 名向 EMU 就诊的个体患者中,仅有 25 名患者(4.8%)有 ADHD 诊断和/或 ADHD 药物的记录(组 II)。组 II 中患者的比例与 EMU 诊断无显著差异。然而,组 II 中的患者有更多的其他精神科诊断(p=0.005)和更多的精神科药物处方(p<0.001)。

结论

我们的研究表明,ADHD 在向 EMU 就诊的患者中被低估和漏诊,筛查工具可能有助于临床医生解决 ADHD 等癫痫共病问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a88/9392548/4bb471b394fe/BRB3-12-e32731-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a88/9392548/4bb471b394fe/BRB3-12-e32731-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a88/9392548/4bb471b394fe/BRB3-12-e32731-g002.jpg

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本文引用的文献

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Screening for adult ADHD using brief rating tools: What can we conclude from a positive screen? Some caveats.使用简短评定工具筛查成人注意缺陷多动障碍:阳性筛查结果能说明什么?一些注意事项。
Compr Psychiatry. 2021 Apr;106:152224. doi: 10.1016/j.comppsych.2021.152224. Epub 2021 Feb 1.
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Attention deficit/hyperactivity disorder and epilepsy.注意缺陷多动障碍与癫痫。
Curr Opin Neurol. 2021 Apr 1;34(2):219-225. doi: 10.1097/WCO.0000000000000903.
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Attention and inhibitory control deficits in patients with genetic generalized epilepsy and psychogenic nonepileptic seizure.
遗传性全面性癫痫与非痫性发作患者的注意与抑制控制缺陷。
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High Yield of Screening for ADHD in the Epilepsy Monitoring Unit.癫痫监测单元中 ADHD 的筛查高产量。
J Atten Disord. 2021 Jun;25(8):1120-1128. doi: 10.1177/1087054719886359. Epub 2019 Nov 9.
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Attention-deficit hyperactivity disorder in adults with epilepsy.成人癫痫伴注意缺陷多动障碍。
Epilepsy Behav. 2019 Dec;101(Pt A):106543. doi: 10.1016/j.yebeh.2019.106543. Epub 2019 Nov 4.
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Links Between Epilepsy and ADHD: Time to Focus and Act.癫痫与注意力缺陷多动障碍之间的联系:是时候关注并采取行动了。
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The Prevalence of "Late-Onset" ADHD in a Clinically Referred Adult Sample.临床就诊成人样本中“晚发”注意缺陷多动障碍的患病率。
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Methylphenidate, cognition, and epilepsy: A 1-month open-label trial.哌甲酯、认知与癫痫:一项为期1个月的开放标签试验。
Epilepsia. 2017 Dec;58(12):2124-2132. doi: 10.1111/epi.13917. Epub 2017 Oct 9.
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Psychiatric and behavioral side effects of antiepileptic drugs in adults with epilepsy.抗癫痫药物在成年癫痫患者中的精神和行为副作用。
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Treatment Controversies in Adult ADHD.成人注意力缺陷多动障碍的治疗争议
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