Virkkunen P, Hietanen P, Nyman M
Strahlenther Onkol. 1987 May;163(5):305-8.
The sizes and locations of pulmonary and pleural metastases in chest X-rays of 50 symptomatic and 65 asymptomatic breast cancer patients were compared and correlated to survival. The diameters of the metastases were about the same in both groups as also their distribution. The incidence of pleural fluid was higher in symptomatic patients. The survival curve of symptomatic patients did not deviate from that of the asymptomatic ones. Symptoms in pulmonary metastatic disease do not mean rapid progress of the disease but may be beneficial in that they cause the patient to visit the oncologist early. The cost-effectiveness of chest X-rays in the follow-up is questionable.
对50例有症状和65例无症状乳腺癌患者胸部X线片中肺和胸膜转移灶的大小及位置进行了比较，并与生存率相关联。两组转移灶的直径及其分布大致相同。有症状患者胸腔积液的发生率更高。有症状患者的生存曲线与无症状患者的生存曲线并无差异。肺转移疾病的症状并不意味着疾病进展迅速，但可能有益，因为它们促使患者尽早就诊肿瘤专科医生。胸部X线片在随访中的成本效益值得怀疑。
