Mathiyazhagan Gopinathan, Gupta Anshul, Rahman Khaliqur, Nityanand Soniya
Department of Hematology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
J Cancer Res Ther. 2022 Apr-Jun;18(3):774-776. doi: 10.4103/jcrt.JCRT_679_20.
Hemophagocytic lymphohistiocytosis (HLH) is a condition characterized by immunological imbalance due to inappropriate activation of macrophage, T/NK cells resulting in hypercytokinemia and subsequent tissue damage. We present an interesting case of acute lymphoblastic leukemia (ALL) who presented to us with clinical and laboratory features of HLH. High index of suspicion for malignancy based on clinical history and bone marrow examination led us to reach at definitive diagnosis of ALL.
噬血细胞性淋巴组织细胞增生症（HLH）是一种由于巨噬细胞、T/NK 细胞的异常激活导致免疫失衡，从而引起细胞因子血症和随后的组织损伤的病症。我们报告了一例有趣的急性淋巴细胞白血病（ALL）病例，该病例以 HLH 的临床和实验室特征就诊。基于临床病史和骨髓检查的高度恶性怀疑，使我们能够明确诊断为 ALL。
