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出生体重在 1000-2000g 之间的婴儿入住希达玛地区哈瓦萨市公立医院新生儿重症监护病房后实现完全肠内喂养的时间的决定因素:一项回顾性队列研究,埃塞俄比亚,2019 年。

Determinants of time to full enteral feeding achievement among infants with birth weight 1000-2000g admitted to the neonatal intensive care unit of public hospitals in Hawassa city, Sidama region Ethiopian, 2019: A retrospective cohort study.

机构信息

Department of Pediatrics and Neonatology, Adare General Hospital, Hawassa, Ethiopia.

Food Science and Nutrition Research Directorate, Ethiopian Public Health Institute (EPHI), Addis Ababa, Ethiopia.

出版信息

PLoS One. 2022 Jul 28;17(7):e0271963. doi: 10.1371/journal.pone.0271963. eCollection 2022.

Abstract

BACKGROUND

Nutritional care during the neonatal period is a cornerstone towards achieving optimal care. However, very limited data is available on optimizing parenteral and enteral nutrition that directly affects infant survival among Ethiopian neonates. Therefore, the objective of this study is to identify determinants of time to full enteral feeding achievement among low-birth-weight neonates admitted to neonatal intensive care units of public hospitals in Hawassa city.

METHODS

A facility-based retrospective cohort study was conducted in Adare general hospital and Hawassa University's comprehensive specialized hospital from August 2018 to 2019. Charts of infants with a birth weight of 1000-2000g (n = 273) neonates who were admitted to the neonatal intensive care unit (ICU) were reviewed. The sample size for each hospital was allocated proportionally and subjects were selected by using a simple random sampling technique. Data were entered using Epi. data version 3.1, and analysis was performed using SPSS version 20. Kaplan-Meier estimator and a Cox proportional hazard model were used.

RESULT

The mean (SD) age when an enteral feed (trophic feeding) was first commenced was 2.13(1.373) days. The median time to achieve full enteral feeding was 8 days with IQR (7-10 days). Gestational age reduces the time to full enteral feeding by 18.8% for each additional week of gestation (AHR = 0.812, p-value = 0.003). The time to achieve full enteral feeding was shorter by 70.4% among neonates who were small for gestational age, as compared with that appropriate for gestational age (AHR = 0.296, p-value<0.001).

CONCLUSION

According to this study, the time that the neonate takes to achieve full enteral feeding was relatively short. Gestational age and weight for gestational were the determinants for time to full enteral feeding achievement. Further research needs to be conducted to explore further, in addition to current findings.

摘要

背景

新生儿期的营养护理是实现最佳护理的基石。然而,关于优化直接影响埃塞俄比亚新生儿存活率的肠外和肠内营养的数据非常有限。因此,本研究的目的是确定在哈瓦萨市公立医院新生儿重症监护病房(NICU)接受治疗的低出生体重儿实现完全肠内喂养的时间的决定因素。

方法

这是一项 2018 年 8 月至 2019 年在阿达尔综合医院和 Hawassa 大学综合专科医院进行的基于设施的回顾性队列研究。对出生体重为 1000-2000 克(n=273)的入住新生儿重症监护病房(NICU)的婴儿的病历进行了回顾。两所医院的样本量按比例分配,并通过简单随机抽样技术选择研究对象。使用 Epi. data 版本 3.1 输入数据,并使用 SPSS 版本 20 进行分析。使用 Kaplan-Meier 估计器和 Cox 比例风险模型进行分析。

结果

开始肠内喂养(营养喂养)的平均(SD)年龄为 2.13(1.373)天。达到完全肠内喂养的中位时间为 8 天,IQR(7-10 天)。每增加一周的胎龄,达到完全肠内喂养的时间就会减少 18.8%(AHR=0.812,p 值=0.003)。与胎龄适当的婴儿相比,小于胎龄儿达到完全肠内喂养的时间缩短了 70.4%(AHR=0.296,p 值<0.001)。

结论

根据这项研究,新生儿达到完全肠内喂养的时间相对较短。胎龄和体重是实现完全肠内喂养时间的决定因素。除了目前的发现,还需要进一步研究来探索更多的内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6c2/9333277/9ab080708203/pone.0271963.g001.jpg

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