Koizumi F, Kawamura T, Ishimori A, Ebina H, Satoh M
Tohoku J Exp Med. 1987 Mar;151(3):275-81. doi: 10.1620/tjem.151.275.
In the present study, pancreatic polypeptide (PP) levels both in basal state and after stimulation by meal were determined in 21 controls, 28 patients with gastric ulcer and 21 patients with duodenal ulcer and their correlation with gastric emptying was examined. In patients with gastric and duodenal ulcers, basal levels as well as stimulated of plasma PP during 95 min of observation period were higher than those in controls except for the values at 5 min. As no correlation was seen between integrated PP response (IPPR) to the meal and T1/2 for gastric emptying in any of three groups, it was indicated that gastric emptying has only a minor role in postprandial PP response.
在本研究中，测定了21名对照组、28名胃溃疡患者和21名十二指肠溃疡患者在基础状态下以及餐后刺激后的胰多肽（PP）水平，并检测了其与胃排空的相关性。在胃溃疡和十二指肠溃疡患者中，除5分钟时的值外，在95分钟观察期内血浆PP的基础水平以及刺激后的水平均高于对照组。由于在三组中的任何一组中，餐后PP综合反应（IPPR）与胃排空的T1/2之间均未发现相关性，表明胃排空在餐后PP反应中仅起次要作用。
