Spine Center, Southeast University Zhongda Hospital, Nanjing, Jiangsu, China.
Department of Orthopedics, Zhongyangmen Community Health Service Center, Gulou, Nanjing, Jiangsu, China.
J Neurol Surg A Cent Eur Neurosurg. 2023 Sep;84(5):433-438. doi: 10.1055/s-0042-1748770. Epub 2022 Jul 28.
In this study, we investigate the effect of simultaneous fusion of preexisting adjacent spinal canal stenosis on the outcome of patients with lumbar spondylolisthesis.
Patients with lumbar spondylolisthesis who underwent transforaminal lumbar interbody fusion (TLIF) from August 2013 to March 2016 were included. The inclusion criteria were the following: single-level spondylolisthesis (L4 or L5) and mild to moderate spinal stenosis at cranial adjacent segment of the spondylolisthesis segment before operation. According to whether the adjacent stenotic segment was included in the scope of surgery, the patients were divided into two groups: group A, only the spondylolisthesis was treated with single-level TLIF, and the adjacent stenosis was not treated with any surgery; In group B, TLIF were performed in the spondylolisthesis segment and the adjacent stenotic level; no spinal stenosis was found in other levels. The patients were followed up for more than 5 years. The general information before operation, visual analog scale (VAS) scores of low back pain and leg pain, and Oswestry disability index (ODI) scores before operation and at the last follow-up were recorded.
A total of 23 patients were included in group A, and 24 patients were included in group B. There was no significant difference between the two groups in gender distribution, age, course of disease, level of slippage, length of stay, degree of spondylolisthesis, stenotic grade of adjacent segment, and intervertebral disk degeneration grade (> 0.05). The blood loss during surgery in group B was significantly higher than that in group A (< 0.05). The operation time of group B was longer than that of group A, but the difference was not statistically significant ( = 0.245). There was no significant difference in preoperative VAS and ODI scores between the two groups. At the last follow-up, the VAS scores of low back pain in the two groups were almost the same. However, the VAS scores of leg pain and ODI scores in group B were slightly higher than those in group A at the last follow-up, but the difference was not statistically significant (> 0.05). If relatives and friends have the similar disease, all the patients of group A and 87.5% of patients in group B would recommend that type of surgery. The satisfaction of group A (100%) was higher than that of group B (79.17%), but the difference was not statistically significant ( = 0.068).
For single-level lumbar spondylolisthesis with mild to moderate spinal stenosis in adjacent segment before operation, decompression and fusion on the level of spondylolisthesis only is a safe, less invasive, and economical surgical option, with good long-term clinical efficacy and high satisfaction rates.
本研究旨在探讨合并术前毗邻椎管狭窄症对腰椎滑脱症患者治疗效果的影响。
纳入 2013 年 8 月至 2016 年 3 月接受经椎间孔腰椎体间融合术(TLIF)治疗的腰椎滑脱症患者。纳入标准为:单节段滑脱(L4 或 L5),术前病变节段颅侧毗邻节段存在轻-中度椎管狭窄。根据毗邻狭窄节段是否包含在手术范围内,将患者分为两组:A 组,仅对滑脱节段行单节段 TLIF,不处理毗邻狭窄;B 组,对滑脱节段及毗邻狭窄节段行 TLIF,其他节段无椎管狭窄。两组患者均随访 5 年以上。记录患者术前一般资料、腰痛及腿痛视觉模拟量表(VAS)评分、Oswestry 功能障碍指数(ODI)评分,以及末次随访时上述指标。
A 组纳入 23 例,B 组纳入 24 例。两组患者性别分布、年龄、病程、滑脱程度、住院时间、滑脱分级、毗邻节段狭窄程度、椎间盘退变分级比较,差异均无统计学意义(>0.05)。B 组手术出血量明显多于 A 组(<0.05)。B 组手术时间长于 A 组,但差异无统计学意义(=0.245)。两组患者术前腰痛、腿痛 VAS 评分及 ODI 评分比较,差异均无统计学意义。末次随访时,两组患者腰痛 VAS 评分基本相同。但 B 组腿痛 VAS 评分及 ODI 评分略高于 A 组,但差异均无统计学意义(>0.05)。如果亲友患有类似疾病,A 组所有患者及 B 组 87.5%的患者均会推荐该术式。A 组患者满意度(100%)高于 B 组(79.17%),但差异无统计学意义(=0.068)。
对于术前毗邻节段存在轻-中度椎管狭窄的单节段腰椎滑脱症,仅行滑脱节段减压融合是一种安全、微创、经济的手术选择,具有良好的长期临床疗效和较高的患者满意度。