Sarkisian T F
Tsitol Genet. 1987 Mar-Apr;21(2):108-11.
The levels of cytogenetic damages in cell cultures of chemical industry workers suffering from different forms of allergy have been investigated. The levels of chromosomal aberrations in cells of allergic patients are shown to reliably increase as against those of healthy donors. Studies on SCE levels have shown no such differences between the patients and donors. The SCE levels have been determined at different periods of BUdR addition and cultures fixation under the effect of environmental factors.
对患有不同形式过敏症的化工行业工人的细胞培养物中的细胞遗传学损伤水平进行了研究。结果表明,与健康供体相比,过敏患者细胞中的染色体畸变水平确实有所增加。对姐妹染色单体交换(SCE)水平的研究表明,患者和供体之间没有这种差异。在环境因素的影响下,已在不同的溴脱氧尿苷(BUdR)添加期和培养物固定期测定了SCE水平。