[培养中细胞分裂时姐妹染色单体交换自发频率水平的降低]
[Decrease in the spontaneous frequency level of sister chromatid exchanges in cell division in culture].
作者信息
Bochkov N P, Chebotarev A N, Platonova V I, Debova G A
出版信息
Tsitol Genet. 1984 Jan-Feb;18(1):54-8.
PMID:6701966
Abstract
The spontaneous level of sister chromatide exchanges (SCE) registered in human lymphocytes is shown to depend on the moment of BUdR introduction and the time of fixation. In early periods of BUdR introduction and fixation the general spontaneous level of SCE may be observed and in later periods only that part of SCE may be registered which is caused by internal conditions. The difference between the first and second results makes the part of SCE conditioned by the environmental effects.
摘要
已表明，在人类淋巴细胞中记录到的姐妹染色单体交换（SCE）自发水平取决于溴脱氧尿苷（BUdR）引入的时间和固定的时间。在引入和固定BUdR的早期，可以观察到SCE的总体自发水平，而在后期，只能记录到由内部条件引起的那部分SCE。这两个结果之间的差异使得SCE的一部分受到环境影响的制约。
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