Gjessing Jensen Karsten
Centre for Child and Adolescent Psychiatry, Capital Region of Copenhagen, Copenhagen Denmark.
Scand J Child Adolesc Psychiatr Psychol. 2022 Jul 3;10(1):87-88. doi: 10.2478/sjcapp-2022-0009. eCollection 2022 Jan.
Increase of serum prolactin is a common adverse effect to antipsychotic medication, potentially leading to galactorrhea, menstrual cycle disturbances or sexual adverse effects. Lurasidone is commonly associated with a low risk of prolactin change.
To describe a case of severe hyperprolactinemia in a 16-year old female with schizophrenia.
Case report.
We saw a severe and sustained prolactin increase during treatment with lurasidone.
Although lurasidone is usually considered not to increase prolactin, some patients may experience this adverse effect. As related subjective consequences may be falsely attributed to the disease or as direct effects of the antipsycotic agent, serum prolactin measurements should be made prior to and during antipsychotic treatment regardless of medication choice.
血清催乳素升高是抗精神病药物常见的不良反应，可能导致溢乳、月经周期紊乱或性功能不良反应。鲁拉西酮通常与催乳素变化风险较低相关。
描述1例16岁患精神分裂症女性的严重高催乳素血症病例。
病例报告。
我们观察到该患者在使用鲁拉西酮治疗期间催乳素出现严重且持续升高。
尽管鲁拉西酮通常被认为不会升高催乳素，但一些患者可能会出现这种不良反应。由于相关主观后果可能被错误地归因于疾病或抗精神病药物的直接作用，无论选择何种药物，在抗精神病治疗前和治疗期间都应检测血清催乳素。
