Ackermann D, Baumann J M
Urol Res. 1987;15(2):63-5. doi: 10.1007/BF00260934.
Variations of urinary pH and concentrations of calcium, phosphate, oxalate, magnesium and citrate have been produced by 4 different diets given to 19 idiopathic calcium stone formers. The state of saturation towards whewellite and brushite was directly measured in the 76 urine samples by equilibration with the corresponding salts and was compared to chemical constituents by regression analyses. The state of saturation towards calcium oxalate monohydrate was significantly governed only by the urinary oxalate concentration, and a soluble oxalate fraction not contributing to calcium oxalate chelation was demonstrated. The state of saturation towards brushite was exclusively determined by urinary calcium and pH, the latter below 5.5 showing a high influence on brushite solubility.
对19名特发性钙结石形成者给予4种不同饮食,从而产生了尿pH值以及钙、磷酸盐、草酸盐、镁和柠檬酸盐浓度的变化。通过与相应盐类平衡,直接测定了76份尿液样本中对水草酸钙和透钙磷石的饱和状态,并通过回归分析将其与化学成分进行比较。一水合草酸钙的饱和状态仅受尿草酸盐浓度的显著影响,并且证明了存在一个对草酸钙螯合无贡献的可溶性草酸盐部分。透钙磷石的饱和状态仅由尿钙和pH值决定,当pH值低于5.5时,对透钙磷石的溶解度有很大影响。