Głuszek J
Department of Internal Diseases, Medical Academy, Poznań, Poland.
Int Urol Nephrol. 1988;20(6):657-64. doi: 10.1007/BF02549499.
The effect of simple carbohydrate intake on the state of urine saturation was studied in 44 patients with calcium kidney stones and in 28 healthy subjects. Renal excretion of calcium, magnesium and oxalate significantly increased and pH of urine decreased after an intake of 100 g glucose in stone formers and healthy subjects. In the basic conditions (before glucose administration) urine was supersaturated with calcium oxalate in stone formers (median 0.55) and healthy subjects (0.24; p less than 0.05). Carbohydrate intake caused a significant increase of the degree of urine saturation with calcium oxalate and uric acid. The degree of urine saturation with brushite and sodium urate after glucose administration did not change. These data suggest that excess of simple carbohydrate consumption may increase the degree of urine saturation with some of the compounds important in stone formation.
在44例肾结石患者和28名健康受试者中研究了简单碳水化合物摄入对尿液饱和状态的影响。结石患者和健康受试者摄入100克葡萄糖后，钙、镁和草酸盐的肾排泄量显著增加，尿液pH值降低。在基础条件下（给予葡萄糖前），结石患者（中位数0.55）和健康受试者（0.24；p<0.05）的尿液草酸钙呈过饱和状态。碳水化合物摄入导致尿液草酸钙和尿酸饱和度显著增加。给予葡萄糖后，透钙磷石和尿酸钠的尿液饱和度未发生变化。这些数据表明，过量摄入简单碳水化合物可能会增加尿液中一些对结石形成重要的化合物的饱和度。
