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基于卷积神经网络算法评估颈椎前路椎间盘切除融合术后融合情况

Assessment of Fusion After Anterior Cervical Discectomy and Fusion Using Convolutional Neural Network Algorithm.

机构信息

Department of Orthopedic Surgery, Dongguk University Ilsan Hospital, Goyang-si, Gyeonggi-do Province, Republic of Korea.

Department of Business Administration, School of Business, Yeungnam University, Gyeongsan-si, Gyeonggi-do Province, Republic of Korea.

出版信息

Spine (Phila Pa 1976). 2022 Dec 1;47(23):1645-1650. doi: 10.1097/BRS.0000000000004439. Epub 2022 Jul 26.

Abstract

BACKGROUND

A convolutional neural network (CNN) is a deep learning (DL) model specialized for image processing, analysis, and classification.

OBJECTIVE

In this study, we evaluated whether a CNN model using lateral cervical spine radiographs as input data can help assess fusion after anterior cervical discectomy and fusion (ACDF).

STUDY DESIGN

Diagnostic imaging study using DL.

PATIENT SAMPLE

We included 187 patients who underwent ACDF and fusion assessment with postoperative one-year computed tomography and neutral and dynamic lateral cervical spine radiographs.

OUTCOME MEASURES

The performance of the CNN-based DL algorithm was evaluated in terms of accuracy and area under the curve.

MATERIALS AND METHODS

Fusion or nonunion was confirmed by cervical spine computed tomography. Among the 187 patients, 69.5% (130 patients) were randomly selected as the training set, and the remaining 30.5% (57 patients) were assigned to the validation set to evaluate model performance. Radiographs of the cervical spine were used as input images to develop a CNN-based DL algorithm. The CNN algorithm used three radiographs (neutral, flexion, and extension) per patient and showed the diagnostic results as fusion (0) or nonunion (1) for each radiograph. By combining the results of the three radiographs, the final decision for a patient was determined to be fusion (fusion ≥2) or nonunion (fusion ≤1). By combining the results of the three radiographs, the final decision for a patient was determined as fusion (fusion ≥2) or nonunion (nonunion ≤1).

RESULTS

The CNN-based DL model demonstrated an accuracy of 89.5% and an area under the curve of 0.889 (95% confidence interval, 0.793-0.984).

CONCLUSION

The CNN algorithm for fusion assessment after ACDF trained using lateral cervical radiographs showed a relatively high diagnostic accuracy of 89.5% and is expected to be a useful aid in detecting pseudarthrosis.

摘要

背景

卷积神经网络(CNN)是一种专门用于图像处理、分析和分类的深度学习(DL)模型。

目的

本研究旨在评估使用侧位颈椎 X 线片作为输入数据的 CNN 模型是否有助于评估前路颈椎间盘切除融合术(ACDF)后的融合情况。

研究设计

使用 DL 的诊断影像学研究。

患者样本

我们纳入了 187 例接受 ACDF 并在术后 1 年进行颈椎 CT 以及中立位和动力位侧位颈椎 X 线片融合评估的患者。

结果测量

基于 CNN 的 DL 算法的性能通过准确性和曲线下面积进行评估。

材料和方法

颈椎 CT 证实融合或不愈合。在 187 例患者中,69.5%(130 例)随机选择为训练集,其余 30.5%(57 例)分配为验证集以评估模型性能。颈椎 X 线片作为输入图像,开发基于 CNN 的 DL 算法。该 CNN 算法每例患者使用三张 X 线片(中立位、前屈位和后伸位),并对每张 X 线片显示的诊断结果为融合(0)或不愈合(1)。通过结合三张 X 线片的结果,确定每位患者的最终决策为融合(融合≥2)或不愈合(融合≤1)。通过结合三张 X 线片的结果,确定每位患者的最终决策为融合(融合≥2)或不愈合(融合≤1)。

结果

基于 CNN 的 DL 模型的准确率为 89.5%,曲线下面积为 0.889(95%置信区间,0.793-0.984)。

结论

使用侧位颈椎 X 线片训练的用于 ACDF 后融合评估的 CNN 算法具有较高的诊断准确率(89.5%),有望成为检测假关节的有用辅助手段。

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