The interplay between disease spreading and awareness diffusion in multiplex networks with activity-driven structure.

The interplay between disease and awareness has been extensively studied in static networks. However, most networks in reality will evolve over time. Based on this, we propose a novel epidemiological model in multiplex networks. In this model, the disease spreading layer is a time-varying network generated by the activity-driven model, while the awareness diffusion layer is a static network, and the heterogeneity of individual infection and recovery ability is considered. First, we extend the microscopic Markov chain approach to analytically obtain the epidemic threshold of the model. Then, we simulate the spread of disease and find that stronger heterogeneity in the individual activities of a physical layer can promote disease spreading, while stronger heterogeneity of the virtual layer network will hinder the spread of disease. Interestingly, we find that when the individual infection ability follows Gaussian distribution, the heterogeneity of infection ability has little effect on the spread of disease, but it will significantly affect the epidemic threshold when the individual infection ability follows power-law distribution. Finally, we find the emergence of a metacritical point where the diffusion of awareness is able to control the onset of the epidemics. Our research could cast some light on exploring the dynamics of epidemic spreading in time-varying multiplex networks.