Area of Toxicology, Department of Health Sciences, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain.
Area of Toxicology, Department of Health Sciences, Faculty of Veterinary Medicine, University of Murcia, 30100 Murcia, Spain; Pollution Diagnostics and Control Group (GDCON), School of the Environment, Faculty of Engineering, University Research Campus (SIU), University of Antioquia (U de A), Calle 70 No. 52-21, Medellin, Colombia.
Mar Pollut Bull. 2022 Sep;182:113973. doi: 10.1016/j.marpolbul.2022.113973. Epub 2022 Jul 28.
Trace elements are pollutants of both natural and anthropogenic origin which can influence negatively on ecosystem and wildlife health. We evaluated trace element in blood samples of gray seal (Halichoerus grypus) stranded in the Gulf of Riga and their influence on their health status through hematological and biochemical profiles. Zn showed the highest levels followed by Cu > Se > Pb > THg > As. Cr and Cd were not detected. Most trace element levels were generally comparable to those reported in seal species; however, high Pb values were observed in those sample showing detectable concentrations (<0.046-257.6 μg/kg ww). Significant positive correlations were found between trace elements concentrations and various biochemical parameters, including Se-ASAT, Se:Hg-ASAT, Cu-TP, Cu-ALB, CuCa, Zn-ALAT, ZN-LDH, ZnP, Zn-Segment neutrophils, and Pb-CK. Nevertheless, most relationships were not strong enough (p > 0.04) to assume a toxicological implication. Despite its limitations, this information could serve as the baseline for future research.
微量元素是自然和人为来源的污染物，它们会对生态系统和野生动物的健康产生负面影响。我们评估了在里加湾搁浅的灰海豹（Halichoerus grypus）血液样本中的微量元素，并通过血液学和生物化学特征来评估它们对健康状况的影响。锌的含量最高，其次是铜>硒>铅>总汞>砷。铬和镉未被检出。大多数微量元素的水平与海豹物种的报道水平相当；然而，在那些可检测浓度（<0.046-257.6μg/kg 湿重）的样本中观察到高铅值。在各种生化参数之间发现了微量元素浓度的显著正相关，包括硒-天门冬氨酸氨基转移酶（ASAT）、硒-汞-天门冬氨酸氨基转移酶（ASAT）、铜-总蛋白（TP）、铜-白蛋白（ALB）、铜-钙（Ca）、锌-丙氨酸氨基转移酶（ALAT）、锌-乳酸脱氢酶（LDH）、锌-碱性磷酸酶（P）、锌-中性粒细胞、铅-肌酸激酶（CK）。然而，大多数关系（p>0.04）都不够强，不能假设存在毒理学意义。尽管存在局限性，但这些信息可以作为未来研究的基础。
