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非闭塞性肠系膜缺血伴显著高磷血症。

Non-occlusive Mesenteric Ischemia with Significant Hyperphosphatemia.

机构信息

Department of Medicine, National Hospital Organization Higashi-ohmi General Medical Center, Japan.

Department of Surgery, National Hospital Organization Higashi-ohmi General Medical Center, Japan.

出版信息

Intern Med. 2023 Mar 1;62(5):729-732. doi: 10.2169/internalmedicine.0074-22. Epub 2022 Jul 29.

DOI:10.2169/internalmedicine.0074-22
PMID:35908963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10037015/
Abstract

An 86-year-old Japanese woman was referred to our hospital due to the sudden onset of abdominal pain. Abdominal contrast-enhanced computed tomography (CT) revealed no signs of ischemic bowel; however, laboratory investigations revealed metabolic lactic acidosis, elevation of inflammatory markers, and a remarkable elevation in the serum phosphate level. A prompt surgical evaluation revealed non-occlusive mesenteric ischemia (NOMI). Elevated serum phosphate levels may suggest extensive bowel ischemia or infarction, which can lead to a prompt surgical evaluation, even in the absence of specific radiological findings.

摘要

一位 86 岁的日本女性因突发腹痛被转至我院。腹部增强 CT 未见缺血性肠病的征象;然而,实验室检查显示代谢性乳酸性酸中毒、炎症标志物升高和血清磷酸盐水平显著升高。及时的外科评估显示非闭塞性肠系膜缺血(NOMI)。血清磷酸盐水平升高可能提示广泛的肠缺血或梗死,即使没有特定的影像学发现,也应及时进行外科评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fd/10037015/d456dac819dc/1349-7235-62-0729-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fd/10037015/7271f344e379/1349-7235-62-0729-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fd/10037015/d456dac819dc/1349-7235-62-0729-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fd/10037015/7271f344e379/1349-7235-62-0729-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24fd/10037015/d456dac819dc/1349-7235-62-0729-g002.jpg

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本文引用的文献

1
Acute Mesenteric Ischemia.急性肠系膜缺血
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2
What affects the prognosis of NOMI patients? Analysis of clinical data and CT findings.哪些因素影响 NOMI 患者的预后?临床资料和 CT 表现分析。
Surg Endosc. 2020 Dec;34(12):5327-5330. doi: 10.1007/s00464-019-07321-9. Epub 2019 Dec 12.
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Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy.非闭塞性肠系膜缺血:病因、诊断及介入治疗
Eur Radiol. 2002 May;12(5):1179-87. doi: 10.1007/s00330-001-1220-2. Epub 2001 Dec 21.
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Changes in body fluid markers in intestinal ischemia.肠道缺血时体液标志物的变化。
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Serum inorganic phosphate levels in experimental intestinal ischaemia.实验性肠缺血时的血清无机磷酸盐水平
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The significance of elevation of serum phosphate levels in experimental intestinal ischemia.实验性肠缺血中血清磷酸盐水平升高的意义
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Value of serum inorganic phosphate in the diagnosis of ischemic bowel disease.血清无机磷在缺血性肠病诊断中的价值
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The significance of elevated peritoneal fluid phosphate level in intestinal infarction.腹腔液磷酸盐水平升高在肠梗死中的意义。
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Preinfarction diagnosis of acute mesenteric ischemia by simple measurement of inorganic phosphate in body fluids.通过简单测量体液中的无机磷酸盐对急性肠系膜缺血进行梗死前诊断。
Can J Surg. 1979 Jan;22(1):40-5.