Sawer B A, Jamieson W G, Durand D
Surg Gynecol Obstet. 1978 Jan;146(1):43-5.
Early diagnosis seems mandatory if the mortality of mesenteric vascular occlusion is to be altered. A model has been developed in which intestinal infarction has been produced by ligation of either the superior mesenteric vein or the superior mesenteric artery. Results of earlier work, using this model, have shown a significant rise in the serum inorganic phosphate level and an associated severe metabolic acidosis. This article has confirmed these results as being statistically significant. In this experiment, a significant rise in the inorganic phosphate level of the peritoneal fluid has been shown in the same model. We suggest that, in the patient with possible intestinal infarction, an elevated serum phosphate level, elevated peritoneal fluid phosphate level, base deficit and leukocytosis may be useful in making an earlier diagnosis of this disease. If an earlier diagnosis is accomplished, the morbidity and mortality of this lethal disease hopefully will be reduced.
如果要改变肠系膜血管闭塞的死亡率，早期诊断似乎是必不可少的。已经建立了一个模型，通过结扎肠系膜上静脉或肠系膜上动脉来制造肠梗死。使用该模型的早期研究结果表明，血清无机磷酸盐水平显著升高，并伴有严重的代谢性酸中毒。本文已证实这些结果具有统计学意义。在本实验中，同一模型显示腹腔液中无机磷酸盐水平显著升高。我们认为，对于可能患有肠梗死的患者，血清磷酸盐水平升高、腹腔液磷酸盐水平升高、碱缺失和白细胞增多可能有助于更早地诊断这种疾病。如果能实现早期诊断，有望降低这种致命疾病的发病率和死亡率。
