Indikt S G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(3):341-3.
The author analyzed the effectivity of the treatment in 602 patients with delirium tremens observed for three years. The first group, 395 patients, received along with the desintoxicational therapy-neuroleptics (aminazin, tizercin, haloperidol). In the second group (207 patients) the treatment was carried out without neuroleptics, the patients received massive desintoxication in the form of drop infusions of solutions with the inclusion of tranquilizers as well (seduxen). The indices of lethality and the average duration of the stay in hospitals were used as criteria of the treatment efficiency. In the second group these indices were much lower: lethality -- 4,4 times less, the duration of the treatment twice less. The data obtained testify against the use of neuroleptics in the treatment of delirium tremens.
作者分析了对602例震颤谵妄患者进行为期三年观察的治疗效果。第一组395例患者,除解毒疗法外还接受了抗精神病药物治疗(氯丙嗪、替泽辛、氟哌啶醇)。第二组(207例患者)未使用抗精神病药物进行治疗,患者接受了大量解毒治疗,采用含镇静剂(安定)的溶液静脉滴注形式。致死率和平均住院时间指标被用作治疗效果的标准。第二组的这些指标要低得多:致死率低4.4倍,治疗时间短两倍。所获得的数据证明在震颤谵妄的治疗中不使用抗精神病药物是合理的。