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[延长药物性睡眠在重症酒精性谵妄患者综合治疗中的应用]

[Prolonged pharmacologic sleep in the complex treatment of patients with severe forms of alcoholic delirium].

作者信息

Danilenko A M, Veselovskiĭ V V, Kuznetsov V I, Vorobeĭchik G N, Tuz M V

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1981;81(7):1064-7.

PMID:6117166
Abstract

Results of treating 235 patients suffering from grave alcohol delirium complicated with somatic pathology are presented. Use was made of various methods of inducing prolonged drug sleep: by neuroleptics, barbiturates with analgesics sodium gamma-hydroxybutyrate alone or in combination with barbiturates or viadril. The method of using the combination of sodium gamma-hydroxybutyrate with barbiturates or viadril G appeared to be the most effective. It use resulted in a rapid elimination of psychomotor excitation, quick induction of deep sleep, considerable shortening of the psychotic period, rapid normalization of vitally important body functions, and shortening of the duration of the post-delirium asthenization.

摘要

本文介绍了对235例患有严重酒精性谵妄并伴有躯体疾病患者的治疗结果。采用了多种诱导长效药物睡眠的方法:使用抗精神病药物、巴比妥类药物与镇痛药、单独使用γ-羟基丁酸钠或与巴比妥类药物或维德雷尔联合使用。γ-羟基丁酸钠与巴比妥类药物或维德雷尔G联合使用的方法似乎是最有效的。其使用导致精神运动性兴奋迅速消除、快速诱导深度睡眠、精神病期显著缩短、重要身体功能迅速恢复正常以及谵妄后虚弱期持续时间缩短。

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