Laboratoire des Interactions Plante-Microbe-Environnement (LIPME), Université de Toulouse, Institut National de Recherche pour l'Agriculture, l'Alimentation, et l'Environnement (INRAE), Centre National de la Recherche Scientifique (CNRS), Castanet Tolosan, France.
Laboratoire des Interactions Plante-Microbe-Environnement (LIPME), Université de Toulouse, Institut National de Recherche pour l'Agriculture, l'Alimentation, et l'Environnement (INRAE), Centre National de la Recherche Scientifique (CNRS), Castanet Tolosan, France.
Trends Plant Sci. 2022 Nov;27(11):1144-1158. doi: 10.1016/j.tplants.2022.06.011. Epub 2022 Jul 28.
Plants are engaged in a coevolutionary arms race with their pathogens that drives rapid diversification and specialization of genes involved in resistance and virulence. However, some major innovations in plant-pathogen interactions, such as molecular decoys, trans-kingdom RNA interference, two-speed genomes, and receptor networks, evolved through the expansion of the functional landscape of genes. This is a typical outcome of genetic co-option, the evolutionary process by which available genes are recruited into new biological functions. Co-option into plant-pathogen interactions emerges generally from (i) cis-regulatory variation, (ii) horizontal gene transfer (HGT), (iii) mutations altering molecular promiscuity, and (iv) rewiring of gene networks and protein complexes. Understanding these molecular mechanisms is key for the functional and predictive biology of plant-pathogen interactions.
植物与其病原体之间存在着协同进化的军备竞赛，这促使与抗性和毒性相关的基因快速多样化和专业化。然而，植物-病原体相互作用中的一些重大创新，如分子诱饵、跨王国 RNA 干扰、双速基因组和受体网络，是通过基因功能景观的扩展而进化的。这是基因共适应的典型结果，即可用基因被招募到新的生物功能中的进化过程。在植物-病原体相互作用中，共适应通常来自 (i) 顺式调控变异，(ii) 水平基因转移 (HGT)，(iii) 改变分子混杂性的突变，以及 (iv) 基因网络和蛋白质复合物的重新布线。理解这些分子机制是植物-病原体相互作用的功能和预测生物学的关键。
