Becher H, Grube E, Lüderitz B
Z Kardiol. 1987 Mar;76(3):182-5.
In a 59-year-old patient with Crohn's disease, tricuspid valve endocarditis caused by candida albicans was observed. Prior to fungal endocarditis a treatment with prednisone and azathioprine was performed. The patient had severe embolic pneumonia with abscesses. Following the echocardiographic examination, the infected valve was replaced by a Hancock bioprosthesis. Despite high dose antifungal chemotherapy the patient died. Septic disorders in patients with Crohn's disease, who are treated with prednisone and azathioprine, can be caused by fungal endocarditis and should be investigated by echocardiography.