Wolf S, Eggert W, Grossmann P, Ditscherlein G, Schneider W
Z Urol Nephrol. 1987 Feb;80(2):97-104.
The blood pressure, urinary symptoms (proteinuria, hematuria, casts), the albumin- and cholesterol concentration in the serum and the renal function (GFR, RPF) of 125 children with chronic glomerulonephritis (GN) were analysed. 76 children had only single symptoms (93% proteinuria, 33% hypertension), which indicated a GN. The serum albumin and cholesterol concentration were pathological in 43% of the patients and serum creatinine level was pathological in 20% of the children. After 6 years the individual courses of renal function demonstrated a deterioration of GFR and RPF for most of the children. It can be concluded, that the summary consideration of epidemiology, symptomatology and renal function of different glomerular lesions has only a limited application to the clinical practice.
对125例慢性肾小球肾炎（GN）患儿的血压、泌尿系统症状（蛋白尿、血尿、管型）、血清白蛋白和胆固醇浓度以及肾功能（肾小球滤过率、肾血浆流量）进行了分析。76例患儿仅有单一症状（93%为蛋白尿，33%为高血压），提示为肾小球肾炎。43%的患者血清白蛋白和胆固醇浓度异常，20%的患儿血清肌酐水平异常。6年后，大多数患儿的肾功能个体病程显示肾小球滤过率和肾血浆流量恶化。可以得出结论，对不同肾小球病变的流行病学、症状学和肾功能进行综合考虑在临床实践中的应用有限。
