Briese V, Brock J
Zentralbl Gynakol. 1987;109(5):280-8.
Single radial immunodiffusion test was used for estimations of IgG, M, A and secretory immunoglobulin A (S-IgA) in cervical secretions of patients with pelvic inflammations. Salpingo-oophoritis was diagnosed and staged by laparoscopy and an activity index aimed controlling the during therapy and decreased after therapy, but the decrease after therapy was significant for IgA only. Immunoglobulin values before and after therapy were as follows: IgG (mean = 0.63 g/l, s = 0.54, n = 32 and x = 0.24 g/l, s = 0.27, n = 7), IgM (mean = 0.028 g/l, s = 0.028, n = 33 and mean = 0.17 g/l, s = 0.023, n = 7), IgA (mean = 0.12 g/l, s = 0.09, n = 30 and mean = 0.04 g/l, s = 0.035, n = 7), S-IgA (mean = 0.77 g/l, s = 0.66 n = 30 and mean = 0.28 g/l, s = 0.41, n = 7). In no case we found an S-IgA deficiency. On the other side IgM could not be estimated in cervical secretions of 8 patients with long time applicated intrauterine device. Therefore IgM in cervical secretions may be a sign of acute ascending inflammations.
采用单向放射免疫扩散试验检测盆腔炎患者宫颈分泌物中的IgG、IgM、IgA和分泌型免疫球蛋白A（S-IgA）。通过腹腔镜检查对输卵管卵巢炎进行诊断和分期，治疗期间使用一个活动指数进行控制，治疗后该指数下降，但仅IgA在治疗后下降显著。治疗前后免疫球蛋白值如下：IgG（均值=0.63g/l，标准差=0.54，n=32；x=0.24g/l，标准差=0.27，n=7），IgM（均值=0.028g/l，标准差=0.028，n=33；均值=0.17g/l，标准差=0.023，n=7），IgA（均值=0.12g/l，标准差=0.09，n=30；均值=0.04g/l，标准差=0.035，n=7），S-IgA（均值=0.77g/l，标准差=0.66，n=30；均值=0.28g/l，标准差=0.41，n=7）。未发现一例S-IgA缺乏情况。另一方面，8例长期使用宫内节育器患者的宫颈分泌物中无法检测到IgM。因此，宫颈分泌物中的IgM可能是急性上行性炎症的一个迹象。
