Miller E C, Abel W
Zentralbl Gynakol. 1984;106(15):1084-91.
Immunoglobulin IgG, IgA and IgM levels in maternal serum of 16 healthy pregnant women are analysed between 7th and 37th week (n = 95) and additionally at second day after delivery. Serum immunoglobulin concentrations of 54 healthy non-pregnant young women are the base for laboratory-specific normal levels. IgA and IgG raise at the beginning of pregnancy and decrease after 17th week; IgA levels after 20th week of pregnancy are not different from concentrations of non-pregnant women. Compared to this, IgG levels fall below the prepregnancy niveau significantly. This continuous decrease lasts anabatedly till the second day following delivery. On the contrary, IgM decrease immediately with starting pregnancy, whereas the following decrease is unessential. After delivery levels rise rapidly. A shortlasting decrease of the concentration of all three immunoglobulins IgG, IgA and IgM with consecutive increase between the 11th and 14th gestational week is a special characteristic sign.
分析了16名健康孕妇在孕7周到37周（共95次检测）期间以及产后第二天母体血清中的免疫球蛋白IgG、IgA和IgM水平。54名健康未孕年轻女性的血清免疫球蛋白浓度作为实验室特定的正常水平基准。IgA和IgG在妊娠初期升高，在第17周后下降；妊娠20周后的IgA水平与未孕女性的浓度无差异。相比之下，IgG水平显著低于孕前水平。这种持续下降在产后第二天才有所缓解。相反，IgM在妊娠开始时立即下降，随后的下降并不明显。产后水平迅速上升。在妊娠第11周到14周期间，所有三种免疫球蛋白IgG、IgA和IgM浓度短暂下降后又连续上升，这是一个特殊的特征性表现。
