Schulze T L, Bosler E M, Shisler J K, Ware I C, Lakat M F, Parkin W E
Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Feb;263(3):427-34. doi: 10.1016/s0176-6724(87)80104-9.
From August 1984 through February 1985, 423 dogs from 43 municipalities in 7 New Jersey counties were evaluated for the presence of antibodies to the Lyme disease spirochete (Borrelia burgdorferi). Of these dogs, 34.7% with no apparent clinical symptoms were serologically reactive (IFA greater than or equal to 1:64); titers in this study ranged from non-reactive to 1:2048. Ninety percent of the dogs surveyed had a current vaccination status to Leptospira interrogans serovars canicola and icterohaemorhagiae. Dogs vaccinated to leptospirosis elicited homologous antibody titers of less than or equal to 1:16 and, therefore, did not interfere with interpretation of antibody levels to B. burgdorferi. Effects of age, degree of outdoor activity, travel history, and location of residence were evaluated. The use of serosurveys of dogs as a tool for Lyme disease surveillance is discussed.
1984年8月至1985年2月,对新泽西州7个县43个自治市的423只狗进行了评估,以检测其是否存在针对莱姆病螺旋体(伯氏疏螺旋体)的抗体。在这些狗中,34.7%无明显临床症状的狗血清学呈反应性(间接荧光抗体试验大于或等于1:64);本研究中的滴度范围从无反应性到1:2048。90%接受调查的狗目前接种了犬型钩端螺旋体和出血性黄疸钩端螺旋体血清型疫苗。接种钩端螺旋体病疫苗的狗产生的同源抗体滴度小于或等于1:16,因此不会干扰对伯氏疏螺旋体抗体水平的解读。评估了年龄、户外活动程度、旅行史和居住地点的影响。讨论了将狗的血清学调查用作莱姆病监测工具的情况。