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[持续性抑郁症患者对具有正负色彩事件的电反应电位]

[Electric reactive potentials to events with a positive and negative coloring in patients with protracted depression].

作者信息

Kurnitskaia I V, Dmitriev A S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(4):589-96.

PMID:3591142
Abstract

The authors measured electrical reactive potentials in the posterior associative and frontal areas, originating in response to winning or losing of the serve in tennis game shown on the video which served as a model of positive and negative emotional reactions. The studied potentials consisted of four waves: P300, N600, P800 and N1000. Healthy subjects experiencing positive emotions showed a more marked negative nature of the potentials in the left posterior associative zone while negative emotions were associated with the presence of predominantly negative potentials in the right frontal area. Patients with protracted depression presented a negative shift of potentials in both right posterior associative zone and left frontal area. The results obtained indicate that protracted depression is attended by impaired topography of the cortical processes associated with positive and negative emotions.

摘要

作者测量了后联合区和额叶区域的电反应电位,这些电位是在观看作为正负情绪反应模型的网球比赛视频中发球的输赢时产生的。所研究的电位由四个波组成:P300、N600、P800和N1000。体验到积极情绪的健康受试者在左后联合区表现出更明显的负性电位,而消极情绪则与右额叶区域主要出现负性电位有关。患有持续性抑郁症的患者在右后联合区和左额叶区域均出现电位负移。获得的结果表明,持续性抑郁症伴随着与正负情绪相关的皮质过程的地形图受损。

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