Lv Qiuyi, Zhang Junning, Pan Yuxing, Liu Xiaodong, Miao Linqing, Peng Jing, Song Lei, Zou Yihuai, Chen Xing
Department of Neurology and Stroke Center, Dongzhimen Hospital, The First Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, China.
Department of Integrative Oncology, China-Japan Friendship Hospital, Beijing, China.
Front Neurol. 2022 Jul 12;13:891283. doi: 10.3389/fneur.2022.891283. eCollection 2022.
Somatosensory deficits after stroke are a major health problem, which can impair patients' health status and quality of life. With the developments in human brain mapping techniques, particularly magnetic resonance imaging (MRI), many studies have applied those techniques to unravel neural substrates linked to apoplexy sequelae. Multi-parametric MRI is a vital method for the measurement of stroke and has been applied to diagnose stroke severity, predict outcome and visualize changes in activation patterns during stroke recovery. However, relatively little is known about the somatosensory deficits after stroke and their recovery. This review aims to highlight the utility and importance of MRI techniques in the field of somatosensory deficits and synthesizes corresponding articles to elucidate the mechanisms underlying the occurrence and recovery of somatosensory symptoms. Here, we start by reviewing the anatomic and functional features of the somatosensory system. And then, we provide a discussion of MRI techniques and analysis methods. Meanwhile, we present the application of those techniques and methods in clinical studies, focusing on recent research advances and the potential for clinical translation. Finally, we identify some limitations and open questions of current imaging studies that need to be addressed in future research.
中风后的体感缺陷是一个重大的健康问题，会损害患者的健康状况和生活质量。随着人类脑图谱技术的发展，尤其是磁共振成像（MRI）技术的发展，许多研究已应用这些技术来揭示与中风后遗症相关的神经基质。多参数MRI是测量中风的重要方法，已被用于诊断中风严重程度、预测预后以及观察中风恢复过程中激活模式的变化。然而，对于中风后的体感缺陷及其恢复情况，人们了解得相对较少。本综述旨在强调MRI技术在体感缺陷领域的实用性和重要性，并综合相关文章以阐明体感症状发生和恢复的潜在机制。在此，我们首先回顾体感系统的解剖和功能特征。然后，我们讨论MRI技术和分析方法。同时，我们介绍这些技术和方法在临床研究中的应用，重点关注近期的研究进展和临床转化潜力。最后，我们指出当前成像研究的一些局限性和有待解决的开放性问题，这些问题需要在未来的研究中加以解决。
