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320 层螺旋 CT 灌注成像在乳腺癌分期及长期动态评估中的价值。

The Value of 320-Slice Spiral Computed Tomography Perfusion Imaging in Staging and Long-Term Dynamic Evaluation of Breast Cancer.

机构信息

Department of Medical Imaging, The First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000 Hebei, China.

Department of Radiotherapy, The First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000 Hebei, China.

出版信息

Comput Math Methods Med. 2022 Jul 21;2022:7442123. doi: 10.1155/2022/7442123. eCollection 2022.

Abstract

The value of 320-slice spiral computed tomography (CT) perfusion imaging in staging and long-term dynamic evaluation of breast cancer was explored. 120 breast cancer patients who underwent preoperative CT examination and were confirmed by surgery and pathology were selected. All patients underwent preoperative TNM staging of breast cancer, with 120 cases in each stage. According to the results of 320-slice spiral CT, the postoperative pathology and surgical methods were compared and analyzed. CT diagnosis of breast cancer showed that T1 sensitivity was 71% and accuracy was 61%, T2 sensitivity was 74% and accuracy was 64%, T3 sensitivity was 94% and the accuracy was 84%, and the T4 sensitivity was 100% and the accuracy was 91%. The sensitivity of N1 stage was 71%, and the accuracy was 61%; and the sensitivity of N2 ~ N3 stage was 81%, and the accuracy was 76%. There were 7 cases of M1 with distant metastasis, the sensitivity was 71%, and the accuracy was 71%. At T1 stage, blood flow (BF) was 39.2 ± 16.7 mL/min/100 g, blood volume (BV) was 2.66 ± 1.4 mL/100 g, mean transit time (MTT) was 8.16 ± 2.7 s, and permeability surface (PS) was 16.6 ± 9.7 mL/min/100 g. 320-slice spiral CT perfusion imaging technology provided a new diagnostic mode for everyone, which can quantitatively identify breast cancer with multiple parameters, which was of great significance for clinical auxiliary diagnosis.

摘要

探讨了 320 层螺旋 CT 灌注成像在乳腺癌分期和长期动态评估中的价值。选取 120 例术前接受 CT 检查并经手术和病理证实的乳腺癌患者。所有患者均行乳腺癌术前 TNM 分期,各期均为 120 例。根据 320 层螺旋 CT 结果,对术后病理和手术方法进行对比分析。CT 诊断乳腺癌 T1 期灵敏度为 71%,准确率为 61%;T2 期灵敏度为 74%,准确率为 64%;T3 期灵敏度为 94%,准确率为 84%;T4 期灵敏度为 100%,准确率为 91%。N1 期的灵敏度为 71%,准确率为 61%;N2~N3 期的灵敏度为 81%,准确率为 76%。有 7 例远处转移的 M1 期,灵敏度为 71%,准确率为 71%。T1 期血流(BF)为 39.2±16.7mL/min/100g,血容量(BV)为 2.66±1.4mL/100g,平均通过时间(MTT)为 8.16±2.7s,通透性表面(PS)为 16.6±9.7mL/min/100g。320 层螺旋 CT 灌注成像技术为大家提供了一种新的诊断模式,能以多种参数定量识别乳腺癌,对临床辅助诊断具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c8b/9334064/d09f33e495c4/CMMM2022-7442123.001.jpg

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