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Metabolic alpha-hydroxylation of the tobacco-specific carcinogen, N'-nitrosonornicotine.

作者信息

Chen C B, Hecht S S, Hoffmann D

出版信息

Cancer Res. 1978 Nov;38(11 Pt 1):3639-45.

PMID:359127
Abstract
摘要

相似文献

1
Metabolic alpha-hydroxylation of the tobacco-specific carcinogen, N'-nitrosonornicotine.
Cancer Res. 1978 Nov;38(11 Pt 1):3639-45.
2
On the metabolic activation of N-nitrosomorpholine and N'-nitrosonornicotine: effects of deuterium substitution.关于N-亚硝基吗啉和N'-亚硝基降烟碱的代谢活化：氘取代的影响。
IARC Sci Publ. 1982(41):499-507.
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Assays for metabolic alpha-hydroxylation of N'-nitrosonornicotine and N-nitrosopyrrolidine and the influence of modifying factors.
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Assay for microsomal alpha-hydroxylation of N'-nitrosonornicotine and determination of the deuterium isotope effect for alpha-hydroxylation.N'-亚硝基降烟碱的微粒体α-羟基化测定及α-羟基化的氘同位素效应测定
Cancer Res. 1979 Dec;39(12):5057-62.
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Stereoselective metabolism of nicotine and tobacco-specific N-nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats.尼古丁和烟草特有N-亚硝胺在大鼠体内立体选择性代谢生成4-羟基-4-(3-吡啶基)丁酸
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6
Metabolic beta-hydroxylation and N-oxidation of N'-nitrosonornicotine.
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7
Comparative carcinogenicity in F344 rats of the tobacco-specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.烟草特异性亚硝胺N'-亚硝基降烟碱和4-(N-甲基-N-亚硝胺基)-1-(3-吡啶基)-1-丁酮在F344大鼠中的致癌性比较
Cancer Res. 1980 Feb;40(2):298-302.
8
Metabolism of the tobacco specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.烟草特异性亚硝胺N'-亚硝基降烟碱和4-(N-甲基-N-亚硝基氨基)-1-(3-吡啶基)-1-丁酮的代谢
IARC Sci Publ. 1980(31):755-65.
9
Effects of dietary compounds on alpha-hydroxylation of N-nitrosopyrrolidine and N'-nitrosonornicotine in rat target tissues.
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10
Effect of nicotine and tobacco-specific nitrosamines on the metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by rat oral tissue.尼古丁和烟草特异性亚硝胺对大鼠口腔组织代谢N'-亚硝基降烟碱和4-(甲基亚硝胺基)-1-(3-吡啶基)-1-丁酮的影响。
Carcinogenesis. 1990 Sep;11(9):1663-6. doi: 10.1093/carcin/11.9.1663.

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Metabolism and DNA Adduct Formation of Tobacco-Specific -Nitrosamines.烟草特有亚硝胺的代谢与 DNA 加合物形成。
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Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N'-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study.烟草特有亚硝胺 N'-亚硝基降烟碱（NNN）的代谢激活与致癌性：密度泛函理论和分子对接研究。
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烟草特异性致癌物N'-亚硝基降烟碱在人体酶系统和大鼠体内经代谢5'-羟基化形成DNA加合物。
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Quantitative analysis of 3'-hydroxynorcotinine in human urine.人尿中3'-羟基去甲可待因的定量分析。
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Protoplasma. 2013 Aug;250(4):919-29. doi: 10.1007/s00709-012-0478-3. Epub 2013 Jan 13.
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Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3263-304. doi: 10.1158/1055-9965.EPI-09-0965.
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