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一种罕见的肾综合征出血热病毒感染继发急性非结石性胆囊炎病例。

A rare case of acute acalculous cholecystitis secondary to hantavirus infection with renal syndrome.

出版信息

Bratisl Lek Listy. 2022;123(10):716-718. doi: 10.4149/BLL_2022_114.

DOI:10.4149/BLL_2022_114
PMID:35913005
Abstract

Hantaviruses are single-stranded RNA viruses. They are transmitted to humans by rodents and insectivore hosts. Some Hantavirus subtypes are the causative agents of haemorrhagic fever with renal syndrome (HFRS), which is characterized by fever, thrombocytopenia, and acute kidney injury. Hantavirus infection is difficult to diagnose due to its non-specific clinical symptoms. Causes of acalculous cholecystitis are severe trauma or burn, surgery, long-term starvation and some viral infections. It is very rare for Hantavirus to cause acute acalculous cholecystitis. The treatment of acute acalculous cholecystitis is usually directed towards its symptoms. A 22-year-old male forest worker was admitted to our emergency outpatient clinic with the complaints of fatigue, oliguria, fever, abdominal pain and vomiting. After the clinical and laboratory examinations, HFRS and acute cholecystitis secondary to Hantavirus infection were diagnosed. The patient's condition and clinical findings improved after supportive treatment. Hantavirus infection should be considered in patients with acute kidney injury, cholecystitis and thrombocytopenia (Fig. 2, Ref. 10). Keywords: Hantavirus, acute kidney injury, acalculous cholecystitis, thrombocytopeni.

摘要

汉坦病毒属于单链 RNA 病毒。它们通过啮齿动物和食虫宿主传播给人类。一些汉坦病毒亚型是肾综合征出血热(HFRS)的病原体,其特征是发热、血小板减少和急性肾损伤。由于其非特异性临床症状,汉坦病毒感染难以诊断。急性非结石性胆囊炎的病因包括严重创伤或烧伤、手术、长期饥饿和某些病毒感染。汉坦病毒很少引起急性非结石性胆囊炎。急性非结石性胆囊炎的治疗通常针对其症状。一名 22 岁的男性林业工人因疲劳、少尿、发热、腹痛和呕吐到我院急诊门诊就诊。经过临床和实验室检查,诊断为汉坦病毒感染引起的 HFRS 和急性胆囊炎。患者经支持治疗后病情和临床症状改善。对于急性肾损伤、胆囊炎和血小板减少症的患者,应考虑汉坦病毒感染(图 2,参考文献 10)。关键词:汉坦病毒、急性肾损伤、非结石性胆囊炎、血小板减少症。

相似文献

1
A rare case of acute acalculous cholecystitis secondary to hantavirus infection with renal syndrome.一种罕见的肾综合征出血热病毒感染继发急性非结石性胆囊炎病例。
Bratisl Lek Listy. 2022;123(10):716-718. doi: 10.4149/BLL_2022_114.
2
[Fulminant acute kidney injury after cholecystectomy in a 45-year-old female patient].[一名45岁女性患者胆囊切除术后发生暴发性急性肾损伤]
Internist (Berl). 2019 Apr;60(4):390-395. doi: 10.1007/s00108-018-0494-2.
3
Acalculous cholecystitis associated with hemorrhagic fever with renal syndrome.无结石性胆囊炎合并肾综合征出血热
Acta Clin Belg. 2015 Oct;70(5):377-81. doi: 10.1179/2295333715Y.0000000028. Epub 2015 May 16.
4
[Hantavirus infection: two case reports from a province in the Eastern Black Sea Region, Turkey].[汉坦病毒感染:来自土耳其黑海东部地区某省的两例病例报告]
Mikrobiyol Bul. 2010 Jul;44(3):479-87.
5
Hantavirus infections.汉坦病毒感染。
Clin Microbiol Infect. 2019 Apr;21S:e6-e16. doi: 10.1111/1469-0691.12291. Epub 2015 Jun 22.
6
Hantavirus Infection in Children-A Pilot Study of Single Regional Center.儿童汉坦病毒感染-单区域中心的初步研究。
Viruses. 2023 Mar 29;15(4):872. doi: 10.3390/v15040872.
7
An adolescent boy with acute kidney injury and fever. Hemorrhagic fever with renal syndrome (HFRS).一名患有急性肾损伤和发热的青少年男性。肾综合征出血热(HFRS)。
Pediatr Nephrol. 2013 Nov;28(11):2113, 2115-6. doi: 10.1007/s00467-012-2359-6. Epub 2012 Nov 14.
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[Acute kidney injury caused by hantavirus in the Netherlands].[荷兰汉坦病毒引起的急性肾损伤]
Ned Tijdschr Geneeskd. 2015;159:A8273.
9
[Hantavirus infections].[汉坦病毒感染]
Rev Med Suisse. 2022 Oct 12;18(799):1900-1903. doi: 10.53738/REVMED.2022.18.799.1900.
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[Acalculous cholecystitis in hantavirus infections].[汉坦病毒感染中的无结石性胆囊炎]
Dtsch Med Wochenschr. 2013 Jun;138(23):1255-8. doi: 10.1055/s-0033-1343197. Epub 2013 May 29.

引用本文的文献

1
Detection of divergent Orthohantavirus tulaense provides insight into wide host range and viral evolutionary patterns.图拉正汉坦病毒的检测为了解其广泛的宿主范围和病毒进化模式提供了线索。
Npj Viruses. 2024 Dec 4;2(1):62. doi: 10.1038/s44298-024-00072-y.