Ohlin H, Mattiasson I, Christensson B, Nyström I, Hood B
Acta Physiol Scand. 1987 Apr;129(4):529-33. doi: 10.1111/j.1748-1716.1987.tb08093.x.
Platelets have the ability to take up, store and release biogenic amines and have therefore been used as models for neurons in studies of neuropsychiatric disorders and hypertension. We have studied the spontaneous efflux of [3H]noradrenaline from platelets and synaptosomes of rats chronically treated with ethanol. Male control rats had a more rapid [3H]noradrenaline efflux both from synaptosomes and platelets than female control rats. Ethanol treatment increased efflux in female rats, again both in platelets and synaptosomes. These results suggest that a parallelism exists in noradrenaline release between synaptosomes and platelets, both basal and in situations which stimulate the release.
血小板具有摄取、储存和释放生物胺的能力，因此在神经精神疾病和高血压研究中被用作神经元模型。我们研究了长期用乙醇处理的大鼠血小板和突触体中[3H]去甲肾上腺素的自发外流。雄性对照大鼠的突触体和血小板中[3H]去甲肾上腺素的外流速度均比雌性对照大鼠快。乙醇处理增加了雌性大鼠血小板和突触体中的外流。这些结果表明，在基础状态和刺激释放的情况下，突触体和血小板之间去甲肾上腺素的释放存在平行关系。
