Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ocul Immunol Inflamm. 2023 Nov;31(9):1750-1757. doi: 10.1080/09273948.2022.2103717. Epub 2022 Aug 1.
To investigate the frequency, clinical findings and outcomes of occlusive retinal vasculitis in patients with multiple sclerosis (MS).
A retrospective case series.
During the period between January 2000 and December 2021, we identified 24 patients who were diagnosed to have uveitis associated with MS. Among them, four (16.6%) patients presented with bilateral occlusive retinal vasculitis who were diagnosed to have MS prior to presentation. All patients were treated successfully with a combination of systemic corticosteroids combined with mycophenolate mofetil. In addition, scatter laser photocoagulation was applied to the ischemic retina in all eyes.
Early recognition and prompt treatment with systemic immunosuppressive agents and scatter laser photocoagulation prevent complications and improve outcomes in MS patients with occlusive retinal vasculitis.
研究多发性硬化症（MS）患者阻塞性视网膜血管炎的频率、临床发现和结果。
回顾性病例系列研究。
在 2000 年 1 月至 2021 年 12 月期间，我们确定了 24 名被诊断为与 MS 相关的葡萄膜炎的患者。其中，4 名（16.6%）患者表现为双侧阻塞性视网膜血管炎，他们在出现症状前被诊断为 MS。所有患者均成功接受了联合全身皮质类固醇和霉酚酸酯治疗。此外，所有患眼均采用散在激光光凝治疗缺血性视网膜。
早期识别和及时使用全身免疫抑制剂和散在激光光凝治疗可预防并发症并改善 MS 患者阻塞性视网膜血管炎的结局。
