Hematology Oncology, Ascension St John Hospital, Detroit, Michigan, USA
Internal Medicine, Ascension St John Hospital, Detroit, Michigan, USA.
BMJ Case Rep. 2022 Aug 1;15(8):e249735. doi: 10.1136/bcr-2022-249735.
Daratumumab-containing regimens are an effective treatment for advanced cases of multiple myeloma. Overall, daratumumab has a favourable safety profile, although rare side effects can occur. Rare side effects of daratumumab include choroidal effusion. Patients who begin to experience symptoms such as eye swelling, vision changes, eye discharge and blurry vision should undergo urgent ophthalmological evaluation and their daratumumab infusions held.
含达雷妥尤单抗的方案是多发性骨髓瘤晚期的有效治疗方法。总体而言,达雷妥尤单抗具有良好的安全性,但也可能出现罕见的副作用。达雷妥尤单抗罕见的副作用包括脉络膜渗出。开始出现眼部肿胀、视力改变、眼部分泌物和视力模糊等症状的患者应立即进行眼科评估,并暂停达雷妥尤单抗输注。