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综合性老年评估和多学科团队干预对住院老年患者的影响(COMPASS):队列内实用试验的方案。

COMPrehensive geriatric AsseSSment and multidisciplinary team intervention for hospitalised older adults (COMPASS): a protocol of pragmatic trials within a cohort.

机构信息

Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Yonsei University College of Nursing, Seoul, Korea.

出版信息

BMJ Open. 2022 Aug 1;12(8):e060913. doi: 10.1136/bmjopen-2022-060913.

Abstract

INTRODUCTION

There is an increased demand for services for hospitalised older patients with acute medical conditions due to rapidly ageing population. The COMPrehensive geriatric AsseSSment and multidisciplinary team intervention for hospitalised older adults (COMPASS) study will test the effectiveness of comprehensive geriatric assessment (CGA) and multidisciplinary intervention by comparing it with conventional care among acute hospitalised older adults in Korea.

METHODS AND ANALYSIS

A multicentre trial within a cohort comprising three substudies (randomised controlled trials) will be conducted. The intervention includes CGA and CGA-based multidisciplinary interventions by physicians (geriatricians, oncologists), nurses, nutritionists and pharmacists. The multidisciplinary intervention includes nutritional support, medication review and adjustment, rehabilitation, early discharge planning and prevention of geriatric syndromes (falls, delirium, pressure sore and urinary retention). The analysis will be based on an intention-to-treat principle. The primary outcome is living at home 3 months after discharge. In addition to assessing the economic effects of the intervention, a cost-utility analysis will be conducted.

ETHICS AND DISSEMINATION

The study protocol was reviewed and approved by the ethics committees of Seoul National University Bundang Hospital and each study site. The study findings will be published in peer-reviewed journals. Subgroup and further in-depth analyses will subsequently be published.

TRIAL REGISTRATION NUMBER

KCT0006270.

摘要

简介

由于人口迅速老龄化,对患有急性内科疾病的住院老年患者的服务需求不断增加。COMPrehensive geriatric AsseSSment and multidisciplinary team intervention for hospitalised older adults(COMPASS)研究将通过比较综合老年评估(CGA)和多学科干预与韩国急性住院老年患者的常规护理,来测试综合老年评估(CGA)和多学科干预的有效性。

方法和分析

将在一项包含三个子研究(随机对照试验)的队列内进行多中心试验。干预措施包括 CGA 和由医生(老年病学家、肿瘤学家)、护士、营养师和药剂师进行的 CGA 为基础的多学科干预。多学科干预包括营养支持、药物审查和调整、康复、早期出院计划和预防老年综合征(跌倒、谵妄、压疮和尿潴留)。分析将基于意向治疗原则。主要结局是出院后 3 个月时居家生活。除了评估干预的经济效果外,还将进行成本-效果分析。

伦理和传播

研究方案已由首尔国立大学盆唐医院和每个研究地点的伦理委员会审查和批准。研究结果将发表在同行评议的期刊上。随后将发表亚组和进一步深入的分析结果。

试验注册号

KCT0006270。

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