Jung Hee-Won, Yoo Hyun-Jung, Park Si-Young, Kim Sun-Wook, Choi Jung-Yeon, Yoon Sol-Ji, Kim Cheol-Ho, Kim Kwang-Il
Geriatric Center, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Korean J Intern Med. 2016 May;31(3):594-600. doi: 10.3904/kjim.2014.331. Epub 2015 Dec 23.
BACKGROUND/AIMS: The fatigue, resistance, ambulation, illnesses, and loss of weight (FRAIL) scale is a screening tool for frailty status using a simple 5-item questionnaire. The aim of this study was to evaluate the clinical feasibility and validity of the Korean version of the FRAIL (K-FRAIL) scale.
Questionnaire items were translated and administered to 103 patients aged ≥ 65 years who underwent a comprehensive geriatric assessment at the Seoul National University Bundang Hospital. In this cross-sectional study, the K-FRAIL scale was compared with the domains and the multidimensional frailty index of the comprehensive geriatric assessment. We also assessed the time required to complete the scale.
The participants' mean age was 76.8 years (standard deviation [SD], 6.1), and 55 (53.4%) were males. The mean overall frailty index was 0.19 (SD, 0.17). For K-FRAIL-robust, prefrail, and frail patients, the mean frailty indices were 0.09, 0.18, and 0.34, respectively (p for trend < 0.001). A higher degree of impairment in the K-FRAIL scale was associated with worse nutritional status, poor physical performance, functional dependence, and polypharmacy. The number of items with impairment in the K-FRAIL scale was positively associated with the frailty index (B = 3.73, p < 0.001). The K-FRAIL scale could differentiate vulnerability from robustness with a sensitivity of 0.90 and a specificity of 0.33. Of all patients, 75 (72.8%) completed the K-FRAIL scale within < 3 minutes.
The K-FRAIL scale is correlated with the frailty index and is a simple tool to screen for frailty in a clinical setting.
背景/目的：疲劳、抵抗力、活动能力、疾病和体重减轻（FRAIL）量表是一种使用简单的5项问卷来筛查衰弱状态的工具。本研究的目的是评估韩文版FRAIL（K-FRAIL）量表的临床可行性和有效性。
对在首尔国立大学盆唐医院接受综合老年评估的103名年龄≥65岁的患者进行问卷项目翻译并发放问卷。在这项横断面研究中，将K-FRAIL量表与综合老年评估的各领域及多维衰弱指数进行比较。我们还评估了完成该量表所需的时间。
参与者的平均年龄为76.8岁（标准差[SD]，6.1），55名（53.4%）为男性。平均总体衰弱指数为0.19（SD，0.17）。对于K-FRAIL量表评定为强壮、前期衰弱和衰弱的患者，平均衰弱指数分别为0.09、0.18和0.34（趋势p<0.001）。K-FRAIL量表中更高程度的损伤与更差的营养状况、较差的身体表现、功能依赖和多重用药相关。K-FRAIL量表中存在损伤的项目数量与衰弱指数呈正相关（B = 3.73，p < 0.001）。K-FRAIL量表能够以0.90的敏感性和0.33的特异性区分脆弱与强壮。在所有患者中，75名（72.8%）在不到3分钟内完成了K-FRAIL量表。
K-FRAIL量表与衰弱指数相关，是在临床环境中筛查衰弱的一种简单工具。
