一例诊断为三重感染（新冠病毒、艾滋病毒和组织胞浆菌病）的继发性噬血细胞性淋巴组织细胞增生症罕见病例
An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis.
作者信息
Touza Masara, Mutyala Monica, Chowdhury Sudipa, Slim Jihad
机构信息
Medicine, Saint George's University School of Medicine, West Indies, GRD.
Infectious Diseases, Saint Michael's Medical Center, Newark, USA.
出版信息
Cureus. 2022 Jun 29;14(6):e26428. doi: 10.7759/cureus.26428. eCollection 2022 Jun.
In this study, we present a unique instance of a patient who developed hemophagocytic lymphohistiocytosis secondary to a triple infection with coronavirus disease 2019 (COVID-19), HIV, and histoplasmosis. We emphasize the proinflammatory dysregulations driving the severity of COVID-19 infection in this setting and highlight the importance of early diagnosis and targeted therapy of underlying conditions as a method to increase the chance of survival.
在本研究中，我们报告了一例独特病例，该患者因2019冠状病毒病（COVID-19）、HIV和组织胞浆菌病三重感染继发噬血细胞性淋巴组织细胞增生症。我们强调了在此情况下驱动COVID-19感染严重程度的促炎调节异常，并强调早期诊断和对基础疾病进行靶向治疗作为提高生存机会的一种方法的重要性。
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