Iron(II)-Catalyzed Nitrene Transfer Reaction of Sulfoxides with -Acyloxyamides.

An iron(II)-catalyzed nitrene transfer reaction of sulfoxides with -acyloxyamides has been developed, leading to the efficient construction of acyl sulfoximines with high functional-group compatibility. The current catalytic transformation was carried out under an air atmosphere at ambient temperature and could be scaled up to gram scale with a catalyst loading of 1 mol %. Application of the methodology was demonstrated by facile C-H acetoxylation and olefination using the acyl sulfoximine as the directing group.