Kojima Hiroyuki, Sofuni Atsushi, Sugimoto Katsutoshi, Tsuchiya Takayoshi, Ishii Kentaro, Tanaka Reina, Tonozuka Ryosuke, Yamamoto Kenjiro, Hirakawa Noriyuki, Itoi Takao
Tokyo Medical University, Gastroenterology and Hepatology, Tokyo, Japan.
J Hepatobiliary Pancreat Sci. 2023 Mar;30(3):351-359. doi: 10.1002/jhbp.1224. Epub 2022 Aug 19.
BACKGROUND/PURPOSE: Shear wave elastography (SWE) is a clinical method used to evaluate liver hardness. In this study, we assessed its applicability in assessing the pancreas and its potential for diagnosing chronic pancreatitis.
We performed SWE on 59 patients who underwent abdominal ultrasound, and measured the computed tomography (CT) values of the pancreas. Patients were classified as having a normal pancreas (NP), early chronic pancreatitis (ECP), or chronic pancreatitis (CP). SW elasticity (SWe), SW dispersion (SWd), and CT values between groups were analyzed.
SWe significantly differed between the CP and NP/ECP groups (NP vs CP; P = 0.001, ECP vs CP; P = 0.026,), while SWd showed a significant difference only between the NP and CP group (NP vs CP; P = 0.001). The CT values were significantly different between the CP and NP/ECP groups (NP vs CP; P = 0.0006, ECP vs CP; P = 0.0027).
Pancreatic SWE and CT values were helpful in the diagnosis of chronic pancreatitis. SWd may reveal status changes in ECP.
背景/目的：剪切波弹性成像（SWE）是一种用于评估肝脏硬度的临床方法。在本研究中，我们评估了其在评估胰腺方面的适用性及其诊断慢性胰腺炎的潜力。
我们对59例行腹部超声检查的患者进行了SWE检查，并测量了胰腺的计算机断层扫描（CT）值。患者被分为胰腺正常（NP）、早期慢性胰腺炎（ECP）或慢性胰腺炎（CP）。分析了各组之间的SW弹性（SWe）、SW离散度（SWd）和CT值。
CP组与NP/ECP组之间的SWe有显著差异（NP与CP比较；P = 0.001，ECP与CP比较；P = 0.026），而SWd仅在NP组和CP组之间有显著差异（NP与CP比较；P = 0.001）。CP组与NP/ECP组之间的CT值有显著差异（NP与CP比较；P = 0.0006，ECP与CP比较；P = 0.0027）。
胰腺SWE和CT值有助于慢性胰腺炎的诊断。SWd可能揭示ECP的状态变化。
